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81623 DEFB126

81623

DEFB126

defensin beta 126

protein-coding

Homo sapiens

基因描述

Type Description
Definition defensin beta 126

研究结论

Date Results Publications
2020-08-22 15:27:00 The role of DEFB126 variation in male infertility and medically assisted reproduction technique outcome. 31474436
2019-08-10 10:18:00 It is a immune component extensively expressed in mucosa and epidermis, which are responsible for the first line of host defense. 30529003
2016-04-02 11:22:00 Data indicate a significant contribution of the frame-shift polymorphism of defensin beta 126 (DEFB126) rs11467497 to male infertility. 25721098
2014-11-05 10:55:00 These results demonstrate that the DEFB126 core peptide has critical functions in parallel to its C-terminal tail by showing LPS-binding activity, anti-inflammatory effects and intracellular regulatory function. In addition, DEFB126 displays antimicrobial activity against E. coli, S. aureus, and C. elegans. 23229569
2013-05-25 11:44:00 This review shows how DEFB126 is critical for efficient transport of sperm in the female reproductive tract, preventing their recognition by the female immune system. 22710670

名称对应

Type IDs
Synonymous C20orf8, DEFB-26, DEFB26, HBD26, bA530N10.1, hBD-26
Gene
UniProtKB-ID: DB126_HUMAN, A0A384MDP8_HUMAN
UniprotKB: Q9BYW3, A0A384MDP8
UniParc: UPI000013CBC7
EMBL: GQ891390, AF525928, AY122478, AL360078, AJ236910
Ensembl: ENSG00000125788
KO: hsa:81623
Nucleutide sequences
EMBL-CDS: CAC27121.1, AAP47221.1, AAM93919.1, ADO22252.1
Ensembl_TRS: ENST00000382398
Protein sequencees
Ensembl_PRO: ENSP00000371835
RefSeq: NP_112193.1
Others
UniRef100: UniRef100_Q9BYW3
UniRef90: UniRef90_Q9BYW3
UniRef50: UniRef50_Q9BYW3
UniGene: Hs.124211
CCDS: CCDS12990.1

全选

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研究热度

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