| Type | Description |
|---|---|
| Definition | chromatin licensing and DNA replication factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:36:00 | Cdt1 mutations found in humans afflicted with Meier-Gorlin syndrome result in either Cdt1/minichromosome maintenance protein binding or cyclin/CDK binding defects | 30281379 |
| 2019-09-28 13:03:00 | Mitotic kinase Aurora B interacts with and phosphorylates Cdt1. Aurora B-phosphomimetic Cdt1 exhibited attenuated MT binding, and its cellular expression induced defective kinetochore-microtubule attachments with a concomitant delay in mitotic progression. | 30154187 |
| 2019-08-03 10:12:00 | The deletion of the entire C-terminal region of Cdt2 decreased its polyubiquitination activity towards Cdt1, resulting in decreased Cdt1 degradation. | 30649446 |
| 2018-09-08 11:49:00 | Results show that both Cdc6 and Cdt1, when expressed in a high level, alone or in combination, were significantly associated with poorer survival in the breast cancer patient cohort. In line with this finding, the expression of Cdc6 and Cdt1 was upregulated in breast cancer cells compared to normal breast epithelial cells. Expression of Cdc6 and Cdt1 was significantly higher in ER negative breast cancer. | 28428557 |
| 2018-05-26 11:39:00 | CDT1, MCM7, and NUDT1 were shown to be up-regulated in hepatocellular carcinoma tissues and provide a more accurate diagnosis than alpha-fetal protein alone. | 29442275 |
| Type | IDs |
|---|---|
| Synonymous | DUP, RIS2 |
| Gene |
UniProtKB-ID:
CDT1_HUMAN
UniprotKB:
Q9H211
UniParc:
UPI00001FF6B1
EMBL:
AC092384,
AF321125,
BC049205,
BC008860,
BC009410,
AB053172,
BC000137,
BC014202,
BC008676,
AF070552
Ensembl:
ENSG00000167513
KO:
hsa:81620
|
| Nucleutide sequences |
EMBL-CDS:
AAG45181.1,
AAH08860.2,
AAH14202.2,
AAH49205.1,
AAH08676.1,
BAB61878.1,
AAH00137.2,
AAH09410.1
Ensembl_TRS:
ENST00000301019
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301019
RefSeq:
NP_112190.2
|
| Others |
UniRef100:
UniRef100_Q9H211
UniRef90:
UniRef90_Q9H211
UniRef50:
UniRef50_Q9H211
UniGene:
Hs.122908
CCDS:
CCDS32510.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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