| Type | Description |
|---|---|
| Definition | factor interacting with PAPOLA and CPSF1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:29:00 | Exquisite response to imatinib mesylate in FIP1L1-PDGFRA-mutated hypereosinophilic syndrome: a 12-year experience of the Polish Hypereosinophilic Syndrome Study Group. | 32125294 |
| 2019-02-16 10:41:00 | Two identified variants revealed novel candidate genes for hip and knee osteoarthritis. OLIG3 and FIP1L1 have specific roles in transcription and may effect expression of other genes. Identified variants in these genes may thus have a role in the regulatory events leading to osteoarthritis. | 30157244 |
| 2019-01-19 10:37:00 | Herein, we report a case of a 53-year-old man with eosinophilia and a well-differentiated extramedullary myeloid tumor with evidence of FIP1L1/PDGFRA rearrangement by fluorescent in situ hybridization in the extramedullary tissue. | 29310833 |
| 2018-08-11 11:13:00 | The authors define the molecular architecture of the core human CPSF complex comprising CPSF160, WDR33, CPSF30 and Fip1 and identify specific domains involved in inter-subunit interactions. Together, these results shed light on the function of CPSF in mediating polyA signal-dependent RNA cleavage and polyadenylation. | 29274231 |
| 2018-04-21 11:10:00 | Case Report: concurrent development of myeloproliferative hypereosinophilic syndrome and lymphomatoid papulosis associated with FIP1L1-PDGFRA gene fusion. | 28374041 |
| Type | IDs |
|---|---|
| Synonymous | FIP1, Rhe, hFip1 |
| Gene |
UniProtKB-ID:
FIP1_HUMAN
UniprotKB:
Q6UN15
UniParc:
UPI0000D9B14D,
UPI0000037BDE,
UPI0000035FBF,
UPI000006F530
EMBL:
AC098587,
BC024016,
AK295737,
AC124017,
AC095040,
AY366510,
AC105384,
AC098821,
BC110383,
AL136910,
AY229892,
BC011543,
BC052959,
AC110298,
CH471057,
AC138607,
AC138779,
BC017724,
AC110792,
AC058822
Ensembl:
ENSG00000145216
KO:
hsa:81608
|
| Nucleutide sequences |
EMBL-CDS:
CAB66844.1,
AAI10384.1,
AAH11543.1,
BAG58575.1,
AAH24016.1,
AAH52959.1,
AAH17724.1,
EAX05448.1,
AAQ88277.1,
AAP69563.1
Ensembl_TRS:
ENST00000358575,
ENST00000507922,
ENST00000337488,
ENST00000306932
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000425456,
ENSP00000336752,
ENSP00000302993,
ENSP00000351383
RefSeq:
NP_001363714.1,
NP_112179.2,
NP_001363688.1,
NP_001363685.1,
NP_001363710.1,
NP_001363679.1,
NP_001363712.1,
NP_001363715.1,
NP_001363690.1,
NP_001363687.1,
NP_001363696.1,
NP_001128409.1,
NP_001363693.1,
NP_001363704.1,
NP_001363694.1,
NP_001363697.1,
NP_001363684.1,
NP_001363675.1,
NP_001363681.1,
NP_001363711.1,
NP_001363709.1,
NP_001363703.1,
NP_001363689.1,
NP_001363713.1,
NP_001363699.1,
NP_001363701.1,
NP_001363683.1,
NP_001363674.1,
NP_001363698.1,
NP_001363680.1,
NP_001363695.1,
NP_001363673.1,
NP_001363707.1,
XP_005265836.1,
NP_001363706.1,
NP_001128410.1,
NP_001363700.1,
NP_001363708.1,
NP_001363677.1,
NP_001363678.1,
XP_016864159.1,
NP_001363702.1,
NP_001363705.1,
NP_001363682.1,
NP_001363686.1,
NP_001363676.1,
NP_001363691.1
|
| Others |
UniRef100:
UniRef100_Q6UN15
UniRef90:
UniRef90_Q6UN15
UniRef50:
UniRef50_Q6UN15
UniGene:
Hs.624245
CCDS:
CCDS3491.1,
CCDS47055.1,
CCDS47056.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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