| Type | Description |
|---|---|
| Definition | tripartite motif containing 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:33:00 | De novo TRIM8 variants impair its protein localization to nuclear bodies and cause developmental delay, epilepsy, and focal segmental glomerulosclerosis. | 33508234 |
| 2021-02-06 13:51:00 | Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis. | 33129786 |
| 2020-10-10 13:02:00 | TRIM8 interacts with KIF11 and KIFC1 and controls bipolar spindle formation and chromosomal stability. | 31904480 |
| 2020-05-16 10:51:00 | The findings uncover a previously unknown regulatory mechanism of type I interferon production in Plasmacytoid dendritic cells by which TRIM8 and Pin1 oppositely regulate the stability of interferon regulatory factor 7. | 31799391 |
| 2019-09-28 12:40:00 | TRIM8 is a novel gene responsible for epileptic encephalopathy, possibly associated with nephrotic syndrome. | 30244534 |
| Type | IDs |
|---|---|
| Synonymous | GERP, RNF27 |
| Gene |
UniProtKB-ID:
TRIM8_HUMAN
UniprotKB:
Q9BZR9
UniParc:
UPI0000134321
EMBL:
AL391121,
BC021925,
AF220034,
CH471066,
AF281046
Ensembl:
ENSG00000171206
KO:
hsa:81603
|
| Nucleutide sequences |
EMBL-CDS:
EAW49680.1,
AAG53488.1,
AAH21925.1,
AAG53087.1
Ensembl_TRS:
ENST00000643721
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000496301
RefSeq:
NP_001332879.1,
NP_112174.2
|
| Others |
UniRef100:
UniRef100_Q9BZR9
UniRef90:
UniRef90_Q9BZR9
UniRef50:
UniRef50_Q9BZR9
UniGene:
Hs.336810
CCDS:
CCDS31274.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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