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81601 Kat5

81601

Kat5

K(lysine) acetyltransferase 5

protein-coding

Mus musculus

基因描述

Type Description
Definition K(lysine) acetyltransferase 5

研究结论

Date Results Publications
2020-10-31 13:13:00 TIP60/KAT5 is required for neuronal viability in hippocampal CA1. 31700011
2020-03-14 12:56:00 These results suggest a concept in which an environment of DNA damage repair, which occurs with decreased KAT5, may affect DNA methylation status. 30699357
2020-02-29 11:31:00 We show that transcriptional activators control BRD4-PTEFb recruitment to E-box-containing circadian promoters. During the activating phase of the circadian cycle, the lysine acetyltransferase TIP60 acetylates the transcriptional activator BMAL1 leading to recruitment of BRD4 and the pause release factor P-TEFb, followed by productive elongation of circadian transcripts 31294688
2019-10-26 11:50:00 that phosphorylation of TIP60 on serines 90 and 86 is important for limiting the accumulation of the pro-end joining factor 53BP1 at DNA double-strand breaks in S and G2 cell cycle phases 30297459
2019-10-26 11:50:00 These findings show that Tip55 is dispensable for the pre- and early post-implantation roles of Kat5, but is essential during organogenesis. 30297694

名称对应

Type IDs
Synonymous AI839539, CPLA2, Htatip, Htatip1, PLIP, Tip55, Tip60
Gene
UniProtKB-ID: KAT5_MOUSE, A0A494BAP7_MOUSE, Q3UJQ1_MOUSE
UniprotKB: Q8CHK4, A0A494BAP7, Q3UJQ1
UniParc: UPI00002264BD, UPI00000E8D67, UPI00000E8E2B, UPI000002956E, UPI000157EE60
EMBL: BC129968, AF528196, AC126029, AF528195, AK146352, AF528194, AY061983, AB055409
Ensembl: ENSMUSG00000024926
KO: mmu:81601
Nucleutide sequences
EMBL-CDS: AAN77140.1, AAI29969.1, AAL34981.1, BAC53807.1, AAN77142.1, AAN77141.1, BAE27104.1
Ensembl_TRS: ENSMUST00000113641, ENSMUST00000236229, ENSMUST00000235701
Protein sequencees
Ensembl_PRO: ENSMUSP00000158391, ENSMUSP00000109271, ENSMUSP00000158181
RefSeq: NP_001186178.1, NP_848752.1, NP_001186176.1, NP_001186177.1, NP_001349299.1, NP_001349301.1, NP_001349300.1, XP_006531923.1
Others
UniRef100: UniRef100_A0A494BAP7, UniRef100_Q8CHK4
UniRef90: UniRef90_A0A337RU94, UniRef90_Q92993
UniRef50: UniRef50_Q8CHK4-3, UniRef50_Q92993
UniGene: Mm.228930
CCDS: CCDS89314.1, CCDS29472.1

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