| Type | Description |
|---|---|
| Definition | p53 and DNA damage regulated 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:54:00 | PDRG1 association with the Wnt signaling pathway in esophageal cancer cells.PDRG1 may promote proliferation while inhibiting apoptosis and chemotherapy sensitivity in esophageal cancer cells. | 31882431 |
| 2020-02-29 10:33:00 | Specific PDRG1 gene silencing may inhibit the growth and metastasis of gastric cancer cells through the activation of ATM/p53 pathway. | 31383535 |
| 2017-02-18 10:28:00 | It was found that PDRG1 could promote radio-resistance that involved the ATM-p53 signaling pathway in lung cancer cells. | 27610824 |
| 2011-07-09 12:18:00 | PDRG1 expression is increased in multiple human malignancies suggesting it to be a high-value novel tumor marker that could play a role in cancer development and/or progression. | 21193842 |
| 2010-01-21 00:00:00 | Cloning and characterization of a novel gene PDRG that is differentially regulated by p53 and ultraviolet radiation | 14562055 |
| Type | IDs |
|---|---|
| Synonymous | C20orf126, PDRG |
| Gene |
UniProtKB-ID:
PDRG1_HUMAN,
A0A384NKN4_HUMAN
UniprotKB:
Q9NUG6,
A0A384NKN4
UniParc:
UPI0000034E24
EMBL:
AK312021,
GQ891341,
CH471077,
AY286301,
BC009334,
BC001856,
AL031658
Ensembl:
ENSG00000088356
KO:
hsa:81572
|
| Nucleutide sequences |
EMBL-CDS:
AAH01856.2,
AAP45329.1,
BAG34958.1,
AAH09334.1,
EAW76399.1,
ADO22203.1
Ensembl_TRS:
ENST00000202017
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000202017
RefSeq:
NP_110442.1
|
| Others |
UniRef100:
UniRef100_Q9NUG6
UniRef90:
UniRef90_Q9NUG6
UniRef50:
UniRef50_Q9NUG6
UniGene:
Hs.435755
CCDS:
CCDS13194.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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