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81565 NDEL1

81565

NDEL1

nudE neurodevelopment protein 1 like 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition nudE neurodevelopment protein 1 like 1

研究结论

Date Results Publications
2020-05-30 12:10:00 DYRK2 phosphorylates NDEL1 S336 to prime the phosphorylation of NDEL1 S332 by GSK3beta. The data suggest the NDEL1 phosphorylation at S336/S332 by the TARA-DYRK2-GSK3beta complex as a novel regulatory mechanism underlying neuronal morphogenesis. 31815665
2019-03-30 11:37:00 observed a positive correlation between Ndel1 activity and the total YMRS score in BD group (p = 0.030) and a positive correlation between ACE activity and Ham-D score 30321766
2018-05-19 11:27:00 Results demonstrate that Ndel1 interacts with Tara to regulate cell movement revealing a novel role of the Ndel1-Tara complex in actin reorganization during cell movement. 27546710
2018-05-05 10:46:00 results highlight S-Nitrosylation as a key activity-dependent mechanism underlying neonatal brain maturation and suggest that reduction of S-Nitrosylation of NDEL1 acts as a pathological factor mediating neurodevelopmental abnormalities caused by maternal alcohol exposure 27371763
2017-12-23 10:51:00 disrupting DISC1/Ndel1 complex formation prolongs mitotic length and interferes with cell-cycle progression in human cells, and it causes cell-cycle deficits of radial glial cells in the embryonic mouse cortex and human forebrain organoids 29103808

名称对应

Type IDs
Synonymous EOPA, MITAP1, NDE1L1, NDE2, NUDEL
Gene
UniProtKB-ID: NDEL1_HUMAN, A6NIZ0_HUMAN
UniprotKB: Q9GZM8, A6NIZ0
UniParc: UPI000268B0E8, UPI000000D76C, UPI0000373E58, UPI0000200937
EMBL: AL832648, AC026130, AK056014, CH471108, AF217798, AY004871, DA256375, BC026101, AF182078
Ensembl: ENSG00000166579
KO: hsa:81565
Nucleutide sequences
EMBL-CDS: BAG51605.1, EAW90051.1, AAG43425.1, AAH26101.1, EAW90052.1, CAD89957.3, AAF24516.3, AAF97497.1
Ensembl_TRS: ENST00000402554, ENST00000334527, ENST00000380025
Protein sequencees
Ensembl_PRO: ENSP00000384963, ENSP00000333982, ENSP00000369364
RefSeq: NP_001317058.1, XP_016880675.1, XP_016880677.1, NP_001020750.1, NP_110435.1, XP_016880673.1, XP_016880674.1, XP_016880672.1, XP_016880676.1
Others
UniRef100: UniRef100_A6NIZ0, UniRef100_Q9GZM8
UniRef90: UniRef90_A6NIZ0, UniRef90_Q9GZM8
UniRef50: UniRef50_A7SPT5, UniRef50_Q9GZM8
UniGene: Hs.372123, Hs.740680
CCDS: CCDS11143.1, CCDS32564.1

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