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81559 TRIM11

81559

TRIM11

tripartite motif containing 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition tripartite motif containing 11

研究结论

Date Results Publications
2020-10-31 13:15:00 TRIM11 promotes lymphomas by activating the beta-catenin signaling and Axin1 ubiquitination degradation. 31786079
2020-07-04 11:47:00 TRIM11 might suppress the translation of DUSP6 via improving its ubiquitination. Additionally, TRIM11 silencing in osteosarcoma (OS) cells significantly reduced its tumorigenicity in vivo. 31950060
2020-02-22 12:50:00 During these processes, TRIM11 interacts with and stabilizes HSF1, increaseing HSF1 levels in the nucleus. These findings identify that TRIM11, through cooperation with HSF1, protects cells against the proteotoxic stress and promotes tumor cell survival. 30563406
2019-08-24 12:25:00 TRIM11 locus is a genetic modifier of progressive supranuclear palsy phenotype. 30066433
2019-06-29 13:09:00 Study detected high expression levels of TRIM11 in breast cancer tissues. Downregulation of TRIM11 in MCF7 and MDAMB231 cells inhibited cell proliferation and promoted cell apoptosis. 30816511

名称对应

Type IDs
Synonymous BIA1, RNF92
Gene
UniProtKB-ID: TRI11_HUMAN
UniprotKB: Q96F44
UniParc: UPI000005340A, UPI0000072358, UPI0000456317
EMBL: AF327056, AK314539, BC011629, BC069227, AK301859, AF220125, AL670729, AK074866, AK097825
Ensembl: ENSG00000154370
KO: hsa:81559
Nucleutide sequences
EMBL-CDS: BAG53535.1, BAG63300.1, BAC11254.1, AAG53498.1, AAH69227.1, BAG37129.1, AAM63957.1, AAH11629.1
Ensembl_TRS: ENST00000284551, ENST00000366699
Protein sequencees
Ensembl_PRO: ENSP00000284551, ENSP00000355660
RefSeq: XP_016857901.1, XP_011542587.1, NP_660215.1
Others
UniRef100: UniRef100_Q96F44
UniRef90: UniRef90_Q99PQ2
UniRef50: UniRef50_Q99PQ2
UniGene: Hs.13543
CCDS: CCDS31048.1

全选

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研究热度

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