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81544 GDPD5

81544

GDPD5

glycerophosphodiester phosphodiesterase domain containing 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition glycerophosphodiester phosphodiesterase domain containing 5

研究结论

Date Results Publications
2018-10-20 11:54:00 Data suggest that GDE2/gdpd5 play roles in pancreatic organogenesis; gdpd5 knockdown leads to defects in differentiation of pancreas in zebrafish embryos; studies with recombinant fusion proteins suggest similar roles for homologous human GDE2 and zebrafish gdpd5. 29203233
2018-10-06 11:56:00 miR-195-5p is a potent suppressor of GDPD5 and that, as such, it significantly increases chemosensitivity and apoptosis in chemoresistant colorectal cells. 29635904
2017-08-26 12:40:00 GDPD5 expression is strongly associated with favorable outcome in neuroblastoma. GDE2 induces differentiation of neuroblastoma cells, suppresses cell motility, and opposes RhoA-driven neurite retraction. 27693046
2013-04-13 12:04:00 Identification of GDPD5 as a glycerophosphocholine phosphodiesterase that probably participates in the regulation of choline phospholipid metabolism in breast cancer. 22279038
2010-01-21 00:00:00 GDPD5 was widely expressed in human tissues and the expression levels in kidney and prostate were relatively low 17578682

名称对应

Type IDs
Synonymous GDE2, PP1665
Gene
UniProtKB-ID: GDPD5_HUMAN
UniprotKB: Q8WTR4
UniParc: UPI0000D62657, UPI000013FBA2, UPI000041BBD3, UPI000013FB97, UPI000013FBBD
EMBL: BC018771, BC033391, AK074848, AF318377, AK098808, AY358477, AF451987, AF318351
Ensembl: ENSG00000158555
KO: hsa:81544
Nucleutide sequences
EMBL-CDS: AAP97686.1, AAL55858.1, AAL55884.1, BAC11242.1, BAC05418.1, AAH33391.1, AAQ88841.1, AAH18771.1
Gene_ORFName: UNQ1850/PRO3580, PP9363, PP6037
Ensembl_TRS: ENST00000533784, ENST00000526177, ENST00000533805, ENST00000336898, ENST00000529721
Protein sequencees
Ensembl_PRO: ENSP00000437049, ENSP00000337972, ENSP00000435196, ENSP00000433214, ENSP00000434050
RefSeq: XP_011543581.1, XP_011543582.1, XP_011543583.1, XP_011543578.1, XP_011543588.1, XP_006718760.1, NP_001338096.1, NP_001338097.1, XP_011543579.1, NP_110419.5, XP_011543580.1
Others
UniRef100: UniRef100_Q8WTR4
UniRef90: UniRef90_Q8WTR4
UniRef50: UniRef50_Q640M6
UniGene: Hs.503297
CCDS: CCDS86230.1, CCDS86229.1, CCDS8238.1

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