例如:"NBL1", "4681", "drought"
收藏
81537 SGPP1

81537

SGPP1

sphingosine-1-phosphate phosphatase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition sphingosine-1-phosphate phosphatase 1

研究结论

Date Results Publications
2018-09-01 10:04:00 the sequential expression and localization of the endogenous S1P regulators SGPP-1 and SGPL-1 and highlight their contribution to the sphingolipid rheostat in inflammation. 29375197
2016-06-11 10:44:00 The two gastric cancer cells transfected with pEF-SGPP1 exhibited a slower rate of growth with less adhesion. Thus, our findings provided evidence that SGPP1 may serve as a prognostic biomarker for patients with advanced gastric cancers. 26239167
2015-11-28 11:23:00 Study has revealed miR-27a as a tumor suppressor and has identified SGPP1 and Smad2 as novel targets of miR-27a, linking to for regulating cancer cell proliferation, apoptosis and migration in colorectal cancer. 25166914
2014-03-01 13:03:00 The sphingolipid phosphatase SGPP1, an antagonist of sphingosine-1-phosphate signaling, is a target of miR-95 that promotes radiation resistance. 24145350
2012-03-24 10:30:00 S1P is elevated in patients with IPF, correlates with the lung function and mediates EMT. 22106015

名称对应

Type IDs
Synonymous SPPase1
Gene
UniProtKB-ID: SGPP1_HUMAN
UniprotKB: Q9BX95
UniParc: UPI000006DEB2
EMBL: AJ293294, CH471061, AK314188, BC063839, AL161670, BC070060, AF349315
Ensembl: ENSG00000285281, ENSG00000126821
KO: hsa:81537
Nucleutide sequences
EMBL-CDS: AAH70060.1, AAH63839.1, EAW80834.1, CAC17772.1, AAK26660.1, BAG36867.1
Ensembl_TRS: ENST00000247225, ENST00000645915
Protein sequencees
Ensembl_PRO: ENSP00000247225, ENSP00000496280
RefSeq: XP_016877167.1, NP_110418.1
Others
UniRef100: UniRef100_Q9BX95
UniRef90: UniRef90_Q9BX95
UniRef50: UniRef50_Q9JI99
UniGene: Hs.24678
CCDS: CCDS9760.1

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

Virginia Commonwealth University School of Medicine

5
2

Biogen Inc., 250 Binney Street, Cambridge, Massachusetts 02142, USA.

1
3

Genoscope-Centre National de Séquençage, 91000, Evry, France. heilig@genoscope.cns.fr

1
4

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

1
5

Max Planck Institute of Biochemistry

1
热点人员
排名 研究人员 文献
1

Sarah Spiegel

4
2

Sheldon Milstien

4
3

Anuradha Madan

3
4

Paola Giussani

3
5

Hervé Le Stunff

3
已经存在同名检索词。
检索词名称不能为空。