| Type | Description |
|---|---|
| Definition | sphingosine-1-phosphate phosphatase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 10:04:00 | the sequential expression and localization of the endogenous S1P regulators SGPP-1 and SGPL-1 and highlight their contribution to the sphingolipid rheostat in inflammation. | 29375197 |
| 2016-06-11 10:44:00 | The two gastric cancer cells transfected with pEF-SGPP1 exhibited a slower rate of growth with less adhesion. Thus, our findings provided evidence that SGPP1 may serve as a prognostic biomarker for patients with advanced gastric cancers. | 26239167 |
| 2015-11-28 11:23:00 | Study has revealed miR-27a as a tumor suppressor and has identified SGPP1 and Smad2 as novel targets of miR-27a, linking to for regulating cancer cell proliferation, apoptosis and migration in colorectal cancer. | 25166914 |
| 2014-03-01 13:03:00 | The sphingolipid phosphatase SGPP1, an antagonist of sphingosine-1-phosphate signaling, is a target of miR-95 that promotes radiation resistance. | 24145350 |
| 2012-03-24 10:30:00 | S1P is elevated in patients with IPF, correlates with the lung function and mediates EMT. | 22106015 |
| Type | IDs |
|---|---|
| Synonymous | SPPase1 |
| Gene |
UniProtKB-ID:
SGPP1_HUMAN
UniprotKB:
Q9BX95
UniParc:
UPI000006DEB2
EMBL:
AJ293294,
CH471061,
AK314188,
BC063839,
AL161670,
BC070060,
AF349315
Ensembl:
ENSG00000285281,
ENSG00000126821
KO:
hsa:81537
|
| Nucleutide sequences |
EMBL-CDS:
AAH70060.1,
AAH63839.1,
EAW80834.1,
CAC17772.1,
AAK26660.1,
BAG36867.1
Ensembl_TRS:
ENST00000247225,
ENST00000645915
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000247225,
ENSP00000496280
RefSeq:
XP_016877167.1,
NP_110418.1
|
| Others |
UniRef100:
UniRef100_Q9BX95
UniRef90:
UniRef90_Q9BX95
UniRef50:
UniRef50_Q9JI99
UniGene:
Hs.24678
CCDS:
CCDS9760.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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