| Type | Description |
|---|---|
| Definition | myocilin |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 10:08:00 | IL-8 increased myocilin expression, Akt phosphorylation, FoxO3 dispersion throughout the cytoplasm, and reduced FoxO3 level. IL-8 decreased the expression of atrogin and MuRF1 and increased myotube length and diameter. | 30945300 |
| 2013-08-31 12:01:00 | Myocilin also stimulated osteogenic differentiation of wild-type MSCs, which was associated with activation of the p38, Erk1/2, and JNK MAP kinase signaling pathways | 23629661 |
| 2010-03-22 11:56:00 | These results demonstrated that the two glaucoma genes, myocilin and optineurin, exhibited differential effects on neurite outgrowth. | 19959812 |
| 2010-01-21 00:00:00 | is a newly identified component of the CNS glial scar that is likely to contribute to neuronal regenerative failure characteristic of the mammalian CNS. | 12799138 |
| 2010-01-21 00:00:00 | No discernible changes in myocilin expression in the chamber angle indicate that myocilin may not be directly linked to ocular hypertension | 16020952 |
| Type | IDs |
|---|---|
| Synonymous | Tigr |
| Gene |
UniProtKB-ID:
MYOC_RAT
UniprotKB:
Q9R1J4
UniParc:
UPI000012FB96
EMBL:
AB019393,
AF093567
KO:
rno:81523
|
| Nucleutide sequences |
EMBL-CDS:
AAD46401.1,
BAA34199.1
|
| Protein sequencees |
RefSeq:
NP_110492.2
|
| Others |
UniRef100:
UniRef100_Q9R1J4
UniRef90:
UniRef90_O70624
UniRef50:
UniRef50_Q99972
UniGene:
Rn.30051
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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