Grb2 - growth factor receptor bound protein 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

收藏

81504 Grb2

基因描述

Type	Description
Definition	growth factor receptor bound protein 2

研究结论

Date	Results	Publications
2021-03-27 14:44:00	Low-magnitude vibration induces osteogenic differentiation of bone marrow mesenchymal stem cells via miR-378a-3p/Grb2 pathway to promote bone formation in a rat model of age-related bone loss.	32652777
2018-03-03 10:19:00	a radical increase in the phosphorylation of IRS2 at serine 731 prevents the recruitment of GRB2 adaptor protein which may fail further to connect the Ras and other pathways required to the cell for its survival and to maintain integrity	28065675
2018-02-03 11:45:00	GRB2 plays an important role in CCl4-induced hepatic fibrosis by regulating hepatic stellate cell function, and up-regulation of GRB2 induced by HMGB1 is mediated via the PI3K/AKT pathway.	28618656
2016-10-22 11:24:00	Growth factor receptor-bound 2 is a direct target of miR-96, which is a negative regulator of cardiac hypertrophy.	26782545
2016-06-28 11:55:00	Study confirmed that miR-19b provided a novel mechanism for regulating liver stellate cells proliferation through the targeting of GRB2.	25650006

名称对应

Type	IDs
Synonymous	Ash-psi
Gene	UniProtKB-ID: GRB2_RAT UniprotKB: P62994 UniParc: UPI000002AABF, UPI000004EF93, UPI000002AABE EMBL: BC091144, D49847, D49846, X62853 Ensembl: ENSRNOG00000003990 KO: rno:81504
Nucleutide sequences	EMBL-CDS: CAA44665.1, BAA08645.1, AAH91144.1, BAA08646.1 Ensembl_TRS: ENSRNOT00000005347
Protein sequencees	Ensembl_PRO: ENSRNOP00000005347 RefSeq: NP_110473.2
Others	UniRef100: UniRef100_P62993 UniRef90: UniRef90_P62993 UniRef50: UniRef50_P62993 UniGene: Rn.3360

全选

{{proteinIndex+1}}

mRNA

Protein

UniprotKB

Description

Refseq

{{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}

Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

收藏到我的文献

全选

Pubmed编号	文献信息	发表日期	相关基因
32652777	Low-magnitude vibration induces osteogenic differentiation of bone marrow mesenchymal stem cells via miR-378a-3p/Grb2 pathway to promote bone formation in a rat model of age-related bone loss. FASEB J Xiaoqin Yu , Ye Zeng , Mingyue Bao , Jirui Wen , Guangguang Zhu , Chengjian Cao , Xueling He , Liang Li	2020-09-01	-
28930697	Overexpression of MUC1 and Genomic Alterations in Its Network Associate with Prostate Cancer Progression. Neoplasia Xiaozeng Lin , Yan Gu , Anil Kapoor , Fengxiang Wei , Tariq Aziz , Diane Ojo , Yanzhi Jiang , Michael Bonert , Bobby Shayegan , Huixiang Yang , Khalid Al-Nedawi , Pierre Major , Damu Tang	2017-11-01	-
28618656	Role of growth factor receptor-bound 2 in CCl₄-induced hepatic fibrosis. Biomed. Pharmacother. Shanfei Ge , Ying Xiong , Xiaoping Wu , Jianping Xie , Fei Liu , Jinni He , Tianxing Xiang , Na Cheng , Lingling Lai , Yuanbin Zhong	2017-08-01	-
28235806	Molecular basis of interactions between SH3 domain-containing proteins and the proline-rich region of the ubiquitin ligase Itch. J Biol Chem Guillaume Desrochers , Laurent Cappadocia , Mathieu Lussier-Price , Anh-Tien Ton , Riham Ayoubi , Adrian Serohijos , James G Omichinski , Annie Angers	2017-04-14	-
28065675	Altered expression of IRS2 and GRB2 in demyelination of peripheral neurons: Implications in diabetic neuropathy. Neuropeptides Mallahalli S Manu , Kuruvanthe S Rachana , Gopal M Advirao	2017-04-01	-
25650006	MicroRNA-19b reduces hepatic stellate cell proliferation by targeting GRB2 in hepatic fibrosis models in vivo and in vitro as part of the inhibitory effect of estradiol. J. Cell. Biochem. Shanfei Ge , Jianping Xie , Fei Liu , Jinni He , Jinwen He	2015-11-01	-
26103942	Grb2 monomer-dimer equilibrium determines normal versus oncogenic function. Nat Commun Zamal Ahmed , Zahra Timsah , Kin M Suen , Nathan P Cook , Gilbert R Lee , Chi-Chuan Lin , Mihai Gagea , Angel A Marti , John E Ladbury	2015-01-01	GRB2
26782545	miR-96 inhibits cardiac hypertrophy by targeting growth factor receptor-bound 2. Genet. Mol. Res. Y Xia , J Sheng , G Y Liang , D X Liu , Q Tang , A P Cheng	2015-01-01	-
23793062	The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells. Nat Immunol Yinming Liang , Margot Cucchetti , Romain Roncagalli , Tadashi Yokosuka , AurÃ©lie Malzac , Elodie Bertosio , Jean Imbert , Isaac J Nijman , Miloslav Suchanek , Takashi Saito , Christoph WÃ¼lfing , Bernard Malissen , Marie Malissen	2013-08-01	-
23533145	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics Simona Principe , E Ellen Jones , Yunee Kim , Ankit Sinha , Julius O Nyalwidhe , Jasmin Brooks , O John Semmes , Dean A Troyer , Raymond S Lance , Thomas Kislinger , Richard R Drake	2013-05-01	-

研究热度

热点单位

排名	科研单位	文献
{{affIndex+1}}	{{aff.value}}	{{aff.size}}

目前还没有研究热点单位

热点人员

排名	研究人员	文献
{{authorIndex+1}}	{{author.value}}	{{author.size}}

目前还没有研究热点人员

© 2017 biocloud.net版权所有 ICP证：京10042835号