DCSTAMP - dendrocyte expressed seven transmembrane protein-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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81501 DCSTAMP

基因描述

Type	Description
Definition	dendrocyte expressed seven transmembrane protein

研究结论

Date	Results	Publications
2020-08-22 15:30:00	Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget's disease of bone.	30705363
2018-06-09 10:56:00	TM7SF4 may be involved in the progression of lung cancer.	28849122
2017-12-02 10:04:00	Our results suggest that the rare genetic variant of TM7SF4 gene, found in our French-Canadian cohort of patients with Paget's disease of bone and which encodes the DC-STAMP protein, increase the number of nuclei per multinucleated cells and affect DC-STAMP expression during osteoclastogenesis in Paget's disease of bone.	29145829
2016-07-30 10:28:00	TM7SF4 plays an essential role in regulating cell cycle progression in breast cancer.	26636523
2015-11-21 11:56:00	The EP in TKA differed from EP in aseptically failed THA by lower CCL3 and DC-STAMP mRNA and protein expression. EP of all studied inflammatory and osteoclastogenic molecules were similar in knee and hip OA.	25151085

名称对应

Type	IDs
Synonymous	FIND, TM7SF4, hDC-STAMP
Gene	UniProtKB-ID: DCSTP_HUMAN UniprotKB: Q9H295 UniParc: UPI0001E8F5D4, UPI000003BCB5 EMBL: AF305068, BC112020, BC171732, AP003471, BC112018, AF277290, BC069349 Ensembl: ENSG00000164935 KO: hsa:81501
Nucleutide sequences	EMBL-CDS: AAL02152.1, AAG39167.1, AAI12019.1, AAI71732.1, AAH69349.1, AAI12021.1 Ensembl_TRS: ENST00000297581, ENST00000517991, ENST00000622554
Protein sequencees	Ensembl_PRO: ENSP00000297581, ENSP00000480546, ENSP00000428869 RefSeq: NP_001244246.1, XP_024303056.1, XP_024303057.1, XP_024303058.1, NP_110415.1, XP_011515623.1, XP_011515626.1
Others	UniRef100: UniRef100_Q9H295 UniRef90: UniRef90_Q9H295 UniRef50: UniRef50_Q9H295 UniGene: Hs.652230, Hs.741954 CCDS: CCDS6301.1, CCDS59111.1

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mRNA

Protein

UniprotKB

Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
30705363	Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget's disease of bone. Sci Rep Benjamin H Mullin , Kun Zhu , Suzanne J Brown , Shelby Mullin , Jennifer Tickner , Nathan J Pavlos , Frank Dudbridge , Jiake Xu , John P Walsh , Scott G Wilson	2019-01-31	-
29145829	Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Paget's disease of bone. BMC Med. Genet. Emilie Laurier , Nathalie Amiable , Edith Gagnon , Jacques P Brown , LaÃ«titia Michou	2017-11-16	-
28849122	Downregulation of TM7SF4 inhibits cell proliferation and metastasis of A549 cells through regulating the PI3K/AKT/mTOR signaling pathway. Mol Med Rep Xudong Yang , Xiaoming Song , Xiaohang Wang , Xiangyan Liu , Zhongmin Peng	2017-11-01	-
26636523	Transmembrane 7 superfamily member 4 regulates cell cycle progression in breast cancer cells. Eur Rev Med Pharmacol Sci X X Zeng , T J Chu , J Y Yuan , W Zhang , Y M Du , Z Y Ban , D M Lei , J Cao , Z Zhang	2015-11-01	-
25891874	Polymorphisms of CSF1 and TM7SF4 genes in a case of mild juvenile Paget's disease found using next-generation sequencing. Croat. Med. J. Judit DonÃ¡th , GÃ¡bor Speer , JÃ¡nos P KÃ³sa , KristÃ³f Ãrvai , Bernadett Balla , PÃ©ter JuhÃ¡sz , PÃ©ter Lakatos , Gyula PoÃ³r	2015-04-01	-
25151085	Comparison of periprosthetic tissues in knee and hip joints: differential expression of CCL3 and DC-STAMP in total knee and hip arthroplasty and similar cytokine profiles in primary knee and hip osteoarthritis. Osteoarthr. Cartil. T Tomankova , E Kriegova , R Fillerova , P Luzna , J Ehrmann , J Gallo	2014-11-01	CCL3, DCSTAMP
24370779	Identification of rare genetic variants in novel loci associated with Paget's disease of bone. Hum. Genet. Mariejka Beauregard , Edith Gagnon , Sabrina Guay-BÃ©langer , Jean Morissette , Jacques P Brown , LaÃ«titia Michou	2014-06-01	-
23525827	Lentivirus-mediated RNA interference of DC-STAMP expression inhibits the fusion and resorptive activity of human osteoclasts. J. Bone Miner. Metab. Zhiyong Zeng , Chenqing Zhang , Junmin Chen	2013-07-01	DCSTAMP
21987375	Regulation of human osteoclast development by dendritic cell-specific transmembrane protein (DC-STAMP). J. Bone Miner. Res. Ya-Hui Chiu , Kofi A Mensah , Edward M Schwarz , Yawen Ju , Masahiko Takahata , Changyong Feng , Loralee A McMahon , David G Hicks , Ben Panepento , Peter C Keng , Christopher T Ritchlin	2012-01-01	-
22058328	The CD40-CD40L axis and IFN-Î³ play critical roles in Langhans giant cell formation. Int. Immunol. Hidemasa Sakai , Ikuo Okafuji , Ryuta Nishikomori , Junya Abe , Kazushi Izawa , Naotomo Kambe , Takahiro Yasumi , Tatsutoshi Nakahata , Toshio Heike	2012-01-01	IFNG, DCSTAMP, CD40, CD40LG

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