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81489 Dnajb1

81489

Dnajb1

DnaJ heat shock protein family (Hsp40) member B1

protein-coding

Mus musculus

基因描述

Type Description
Definition DnaJ heat shock protein family (Hsp40) member B1

研究结论

Date Results Publications
2018-07-07 11:58:00 Study validates the DNAJB1-PRKACA fusion kinase as an oncogenic driver and candidate drug target for fibrolamellar hepatocellular carcinoma in mouse model in which tumorigenesis was significantly enhanced by genetic activation of beta-catenin. 29162699
2017-12-09 11:29:00 Generation of the Dnajb1-Prkaca fusion gene in wild-type mice to be sufficient to initiate formation of tumors that have many features of human fibrolamellar hepatocellular carcinonma. 28923495
2017-06-24 10:13:00 Overexpression of DNAJB1 relieves TDP-43 mediated toxicity in primary rodent cortical neurons. 28531192
2012-11-03 13:27:00 a biochemical link between Hsp40 expression and Abeta(42) proteostasis that is cell specific 22666389
2011-12-10 12:05:00 Hsc70, Hdj1 and Hdj2 interact with soluble and fibrillar alpha-synuclein 21832061

名称对应

Type IDs
Synonymous 0610007I11Rik, DjB1, HSPF1, Hdj1, Hsp40
Gene
UniProtKB-ID: DNJB1_MOUSE, Q3TU79_MOUSE, Q3TYL7_MOUSE
UniprotKB: Q9QYJ3, Q3TU79, Q3TYL7
UniParc: UPI0000001929, UPI00005AD1F0
EMBL: AB028273, BC012962, AB028272, AK158530, AK160924, AC151992, AK146657, AK164392
Ensembl: ENSMUSG00000005483
KO: mmu:81489
Nucleutide sequences
EMBL-CDS: AAH12962.1, BAA95672.1, BAA88083.1, BAE27337.1, BAE37769.1, BAE36092.1, BAE34546.1
Ensembl_TRS: ENSMUST00000005620, ENSMUST00000212300
Protein sequencees
Ensembl_PRO: ENSMUSP00000005620, ENSMUSP00000148685
RefSeq: NP_061278.1, NP_001295156.1
Others
UniRef100: UniRef100_Q9QYJ3
UniRef90: UniRef90_P25685
UniRef50: UniRef50_P25685
UniGene: Mm.282092
CCDS: CCDS22456.1

全选

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