| Type | Description |
|---|---|
| Definition | RNA polymerase II subunit M |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 10:41:00 | The relatively slow functional loading of Gdown1 in the presence of TFIIF. | 27716820 |
| 2014-08-09 12:27:00 | Data indicate that phosphorylation of Gdown1 on Ser-270 reduces Its affinity for RNA polymerase II. | 24634214 |
| 2014-06-07 11:27:00 | Modification of TFIIF provides one pathway through which efficient Gdown1 loading can occur early in elongation, allowing downstream pausing to be regulated. | 24596085 |
| 2012-03-31 10:05:00 | Gdown1 stabilizes poised polymerases while maintaining their responsiveness to P-TEFb. | 22244331 |
| 2012-03-31 10:05:00 | Gdown1 competes with TFIIF for binding to the RPB1 and RPB5 subunits of Pol II, thereby inhibiting an essential function of TFIIF in preinitiation complex assembly. | 22244332 |
| Type | IDs |
|---|---|
| Synonymous | GCOM1, GRINL1A, Gdown, Gdown1 |
| Gene |
UniProtKB-ID:
GL1AD_HUMAN,
MYZAP_HUMAN,
GRL1A_HUMAN
UniprotKB:
Q6EEV4,
P0CAP1,
P0CAP2
UniParc:
UPI00004089BA,
UPI00003BE8EB,
UPI00001C1047,
UPI00003BE8E6,
UPI000000D78C,
UPI0000375B73,
UPI00003BE8E1,
UPI00003BE8E2,
UPI00003BE8E3,
UPI00003BE8E7,
UPI00003BE8E0,
UPI000004EE89,
UPI00003BE8E5,
UPI00001FE55B,
UPI0000375B72,
UPI00003BE8E4
EMBL:
AK128618,
AC025271,
AY353061,
CH471082,
AY341344,
AY334560,
AK074767,
AF326773,
BC112148,
AK074955,
AY333779,
AY331564,
AY353056,
AC090651,
AY353057,
BC101645,
AY207007,
AY353058,
AY334561,
AY237639,
AY353060,
BC001510,
FJ970029,
AY207459,
AY208913,
AY341345,
AL050091,
AY339380,
AY334562,
AK055535
Ensembl:
ENSG00000263155,
ENSG00000255529
KO:
hsa:81488,
hsa:145781,
hsa:100820829
|
| Nucleutide sequences |
EMBL-CDS:
AAQ76830.1,
AAQ82540.1,
AAQ76836.1,
AAQ76834.1,
ADA68358.1,
AAQ76825.1,
AAP41549.1,
AAQ76828.1,
AAP41548.1,
BAB70944.1,
AAQ76827.1,
EAW77527.1,
AAI12149.1,
AAO39707.1,
AAQ76833.1,
AAI01646.1,
AAP75897.1,
AAQ76831.1,
AAQ76826.1,
AAQ76832.1,
AAQ76829.1,
EAW77522.1,
AAH01510.1,
CAB43263.1,
EAW77525.1,
AAQ76837.1,
BAC11193.1,
AAK92284.2,
AAO39707.1,
BAC11313.1,
BAC87533.1
Ensembl_TRS:
ENST00000649091,
ENST00000267853,
ENST00000380565,
ENST00000482852,
ENST00000380557,
ENST00000299638
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497820,
ENSP00000369939,
ENSP00000267853,
ENSP00000369930,
ENSP00000432615,
ENSP00000299638
RefSeq:
NP_001018112.1,
NP_056347.1
|
| Others |
UniRef100:
UniRef100_P0CAP2,
UniRef100_Q6EEV4,
UniRef100_P0CAP1
UniRef90:
UniRef90_P0CAP1,
UniRef90_P0CAP2,
UniRef90_Q6EEV4
UniRef50:
UniRef50_P0CAP1,
UniRef50_Q6EEV4,
UniRef50_P0CAP2
UniGene:
Hs.437256
CCDS:
CCDS42044.1,
CCDS10162.1,
CCDS42045.1,
CCDS32252.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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