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814364 PF3D7_0304600

814364

PF3D7_0304600

circumsporozoite (CS) protein

protein-coding

Plasmodium falciparum 3D7

基因描述

Type Description
Definition circumsporozoite (CS) protein

研究结论

Date Results Publications
2018-02-03 12:03:00 The circumsporozoite protein (CSP) and the thrombospondin-related anonymous protein (TRAP) bind to the heparan sulfate proteoglycan on the hepatocyte surface and contribute to sporozoite infection and hepatocyte selectivity. 27007512
2016-02-20 10:23:00 CSP is N-terminally processed in the mosquito host and undergoes a reversible conformational change to mask some epitopes in the N- and C-terminal domains until the sporozoite interacts with the liver hepatocyte. 26169272
2015-11-07 11:04:00 An unstable Th epitope of P. falciparum fosters central memory T cells and anti-CS antibody responses. 24983460
2014-08-30 12:34:00 Data indicate that the self-assembling protein nanoparticle (SAPN) vaccine construct induces long-lasting antibody and cellular immune responses to epitope specific sequences of the circumsporozoite protein (PfCSP). 23144750
2013-05-18 10:29:00 Data indicate that the circumsporozoite protein (PfCSP) in sporozoite (PfSPZ) was highly sensitive and reproducible measured by the assay. 23399449

名称对应

Type IDs
Synonymous PFC0210c
Gene
UniProtKB-ID: Q7K740_PLAF7
UniprotKB: Q7K740
UniParc: UPI000000D3F8
EMBL: AL844502
EnsemblGenome: PF3D7_0304600
KO: pfa:PF3D7_0304600
Nucleutide sequences
EMBL-CDS: CAB38998.2
Gene_ORFName: PF3D7_0304600
Protein sequencees
RefSeq: XP_001351122.1
Others
UniRef100: UniRef100_P19597
UniRef90: UniRef90_P19597
UniRef50: UniRef50_P19597

全选

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研究热度

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