Type | Description |
---|---|
Definition | cytoadherence linked asexual protein 3.1 |
Date | Results | Publications |
---|---|---|
2019-02-02 10:46:00 | CLAG3 undergoes self-association and that this protein's expression determines channel phenotype quantitatively. | 29739907 |
2017-07-22 11:38:00 | RHOPH1 participates in multiple high molecular weight complexes, one of which localizes to the erythrocyte surface. This 480kDa complex, likely composed of an oligomerized version of 160kDa RHOPH1, is integral to the erythrocyte membrane and thus serves as an attractive candidate as the possible pore of Plasmodial Surface Anion Channel. | 27299521 |
2014-05-10 11:01:00 | These results demonstrate that malaria parasites can become resistant to toxic compounds such as drugs by epigenetic switches in the expression of clag3 genes necessary for the formation of solute channels. | 23819786 |
2011-08-06 11:13:00 | DNA transfection and in vitro selections indicate that plasmodial surface anion channel-inhibitor interactions are encoded by two clag3 genes previously assumed to function in cytoadherence. | 21620134 |
2011-07-30 11:10:00 | These clag 3-null parasites demonstrate a significant growth inhibition compared with wild-type parasites, providing the first genetic evidence for a role for these proteins in efficient parasite proliferation. | 21320181 |
Type | IDs |
---|---|
Synonymous | PFC0120w |
Gene |
UniProtKB-ID:
O77310_PLAF7
UniprotKB:
O77310
UniParc:
UPI000007E82E
EMBL:
AL844502
EnsemblGenome:
PF3D7_0302500
KO:
pfa:PF3D7_0302500
|
Nucleutide sequences |
EMBL-CDS:
CAB10572.2
Gene_ORFName:
PF3D7_0302500
|
Protein sequencees |
RefSeq:
XP_001351100.1
|
Others |
UniRef100:
UniRef100_A0A2I0BTS3
UniRef90:
UniRef90_A0A1W6IZK1
UniRef50:
UniRef50_A0A2P9CHQ3
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
29739907 |
mBio Ankit Gupta , Praveen Balabaskaran-Nina , Wang Nguitragool , Gagandeep S Saggu , Marc A Schureck , Sanjay A Desai |
2018-05-08 | - |
27299521 |
PLoS ONE Kayvan Zainabadi |
2016-01-01 | - |
23819786 |
Epigenetic switches in clag3 genes mediate blasticidin S resistance in malaria parasites. Cell. Microbiol. SofÃa Mira-MartÃnez , Núria Rovira-Graells , Valerie M Crowley , Lindsey M Altenhofen , Manuel Llinás , Alfred Cortés |
2013-11-01 |
RhopH1(3.1)
|
21620134 |
Malaria parasite clag3 genes determine channel-mediated nutrient uptake by infected red blood cells. Cell Wang Nguitragool , Abdullah A B Bokhari , Ajay D Pillai , Kempaiah Rayavara , Paresh Sharma , Brad Turpin , L Aravind , Sanjay A Desai |
2011-05-27 | - |
21320181 |
Mol Microbiol Christy A Comeaux , Bradley I Coleman , Amy K Bei , Nicole Whitehurst , Manoj T Duraisingh |
2011-04-01 | - |
16267556 |
A protein interaction network of the malaria parasite Plasmodium falciparum. Nature Douglas J LaCount , Marissa Vignali , Rakesh Chettier , Amit Phansalkar , Russell Bell , Jay R Hesselberth , Lori W Schoenfeld , Irene Ota , Sudhir Sahasrabudhe , Cornelia Kurschner , Stanley Fields , Robert E Hughes |
2005-11-03 |
MAL7P1.109,
MAL7P1.19,
MAL7P1.10,
MAL7P1.102,
PF07_0006,
PF07_0012,
PF07_0016,
MAL7P1.167,
MAL7P1.17,
MAL7P1.170,
MAL7P1.171,
MAL7P1.172,
MAL7P1.173,
MAL7P1.174,
ERF2,
MAL7P1.7,
MAL7P1.147,
MAL7P1.155,
MAL7P1.16,
MAL7P1.160,
MAL7P1.76,
MAL7P1.77,
MAL7P1.81,
MAL7P1.86,
PF07_0020,
PF07_0021,
PF07_0023,
PF07_0024,
PF07_0026,
PF07_0029,
PF07_0033,
MAL7P1.132,
MAL7P1.134,
MAL7P1.141,
MAL7P1.145,
PF07_0042,
PF07_0043,
PF07_0044,
PF07_0047,
PF07_0053,
PF07_0056,
PF07_0057,
PF07_0062,
PF07_0066,
PF07_0067,
PF07_0071,
PfCDPK4,
PF07_0073,
PF07_0077,
PF07_0080,
PF07_0081,
PF07_0082,
PF07_0084,
PF07_0086,
PF07_0087,
PF07_0088,
PF07_0097,
PF07_0100,
PF07_0101,
MAL7P1.126,
MAL7P1.129,
MAL7P1.13,
PF07_0104,
PF07_0105,
PF07_0106,
PF07_0107,
PF07_0112,
PF07_0117,
PF07_0120,
PF07_0122,
PF07_0123,
ApiAP2,
MAL7P1.118,
MAL7P1.119,
MAL7P1.12,
MAL7P1.20,
PfORC2,
MAL7P1.24,
MAL7P1.30,
MAL7P1.37,
MAL7P1.38,
MAL8P1.103,
MAL8P1.104,
MAL8P1.23,
MAL8P1.111,
MAL8P1.113,
MAL8P1.12,
2255.m00020,
MAL8P1.125,
MAL8P1.127,
MAL8P1.128,
PF08_0054,
PF08_0055,
PF08_0058,
PF08_0059,
PF08_0060,
PF08_0068,
PF08_0075,
PF08_0076
|
15953647 |
Mol. Biochem. Parasitol. Osamu Kaneko , Brian Y S Yim Lim , Hideyuki Iriko , Irene T Ling , Hitoshi Otsuki , Munira Grainger , Takafumi Tsuboi , John H Adams , Denise Mattei , Anthony A Holder , Motomi Torii |
2005-09-01 | - |
12368867 |
Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature N Hall , A Pain , M Berriman , C Churcher , B Harris , D Harris , K Mungall , S Bowman , R Atkin , S Baker , A Barron , K Brooks , C O Buckee , C Burrows , I Cherevach , C Chillingworth , T Chillingworth , Z Christodoulou , L Clark , R Clark , C Corton , A Cronin , R Davies , P Davis , P Dear , F Dearden , J Doggett , T Feltwell , A Goble , I Goodhead , R Gwilliam , N Hamlin , Z Hance , D Harper , H Hauser , T Hornsby , S Holroyd , P Horrocks , S Humphray , K Jagels , K D James , D Johnson , A Kerhornou , A Knights , B Konfortov , S Kyes , N Larke , D Lawson , N Lennard , A Line , M Maddison , J McLean , P Mooney , S Moule , L Murphy , K Oliver , D Ormond , C Price , M A Quail , E Rabbinowitsch , M-A Rajandream , S Rutter , K M Rutherford , M Sanders , M Simmonds , K Seeger , S Sharp , R Smith , R Squares , S Squares , K Stevens , K Taylor , A Tivey , L Unwin , S Whitehead , J Woodward , J E Sulston , A Craig , C Newbold , B G Barrell |
2002-10-03 |
MAL7P1.110,
MAL7P1.113,
MAL7P1.104,
MAL7P1.93,
MAL7P1.94,
PF07_0005,
PF07_0014,
MAL7P1.162,
MAL7P1.164,
MAL7P1.4,
MAL7P1.69,
MAL7P1.73,
MAL7P1.147,
MAL7P1.150,
MAL7P1.151,
MAL7P1.161,
MAL7P1.75,
MAL7P1.81,
MAL7P1.86,
PF07_0021,
PF07_0023,
PF07_0027,
PF07_0040,
MAL7P1.137,
MAL7P1.139,
MAL7P1.145,
PF07_0046,
PF07_0047,
PF07_0054,
PF07_0057,
PF07_0059,
PF07_0062,
PF07_0065,
PF07_0070,
PF07_0071,
PfCDPK4,
PF07_0073,
PF07_0079,
PF07_0080,
PF07_0085,
PF07_0086,
PF07_0088,
PF07_0091,
PF07_0098,
MAL7P1.130,
PF07_0103,
PF07_0105,
PF07_0112,
PF07_0115,
PF07_0117,
PF07_0123,
MAL7P1.118,
MAL7P1.12,
MAL7P1.122,
MAL7P1.20,
PfCRT,
MAL7P1.37,
MAL7P1.38,
MAL8P1.13,
MAL8P1.131,
MAL8P1.23,
MAL8P1.12,
MAL8P1.125,
MAL8P1.128,
MAL8P1.110,
PF08_0055,
PF08_0056,
PF08_0059,
PF08_0069,
FeSOD,
PF08_0075,
PF08_0076,
PF08_0084,
PF08_0085,
PF08_0096,
PF08_0108,
PF08_0126,
PF08_0129,
PF08_0132,
PF08_0136b,
MAL8P1.48,
MAL8P1.51,
MAL8P1.37,
MAL8P1.40,
MAL8P1.43,
MAL8P1.108,
MAL8P1.140,
MAL8P1.3,
MAL8P1.31,
MAL8P1.32,
MAL8P1.33,
MAL8P1.76,
MAL8P1.78,
MAL8P1.83,
MAL8P1.9,
PF08_0006,
PF08_0009,
PF08_0011,
PF08_0014
|
10448855 |
The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum. Nature S Bowman , D Lawson , D Basham , D Brown , T Chillingworth , C M Churcher , A Craig , R M Davies , K Devlin , T Feltwell , S Gentles , R Gwilliam , N Hamlin , D Harris , S Holroyd , T Hornsby , P Horrocks , K Jagels , B Jassal , S Kyes , J McLean , S Moule , K Mungall , L Murphy , K Oliver , M A Quail , M A Rajandream , S Rutter , J Skelton , R Squares , S Squares , J E Sulston , S Whitehead , J R Woodward , C Newbold , B G Barrell |
1999-08-05 | - |
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