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814342 PF3D7_0302500

814342

PF3D7_0302500

cytoadherence linked asexual protein 3.1

protein-coding

Plasmodium falciparum 3D7

基因描述

Type Description
Definition cytoadherence linked asexual protein 3.1

研究结论

Date Results Publications
2019-02-02 10:46:00 CLAG3 undergoes self-association and that this protein's expression determines channel phenotype quantitatively. 29739907
2017-07-22 11:38:00 RHOPH1 participates in multiple high molecular weight complexes, one of which localizes to the erythrocyte surface. This 480kDa complex, likely composed of an oligomerized version of 160kDa RHOPH1, is integral to the erythrocyte membrane and thus serves as an attractive candidate as the possible pore of Plasmodial Surface Anion Channel. 27299521
2014-05-10 11:01:00 These results demonstrate that malaria parasites can become resistant to toxic compounds such as drugs by epigenetic switches in the expression of clag3 genes necessary for the formation of solute channels. 23819786
2011-08-06 11:13:00 DNA transfection and in vitro selections indicate that plasmodial surface anion channel-inhibitor interactions are encoded by two clag3 genes previously assumed to function in cytoadherence. 21620134
2011-07-30 11:10:00 These clag 3-null parasites demonstrate a significant growth inhibition compared with wild-type parasites, providing the first genetic evidence for a role for these proteins in efficient parasite proliferation. 21320181

名称对应

Type IDs
Synonymous PFC0120w
Gene
UniProtKB-ID: O77310_PLAF7
UniprotKB: O77310
UniParc: UPI000007E82E
EMBL: AL844502
EnsemblGenome: PF3D7_0302500
KO: pfa:PF3D7_0302500
Nucleutide sequences
EMBL-CDS: CAB10572.2
Gene_ORFName: PF3D7_0302500
Protein sequencees
RefSeq: XP_001351100.1
Others
UniRef100: UniRef100_A0A2I0BTS3
UniRef90: UniRef90_A0A1W6IZK1
UniRef50: UniRef50_A0A2P9CHQ3

全选

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研究热度

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