PF3D7_1350100 - lysine--tRNA ligase-BMKCloudï½ç¾è¿å®¢äº

814227 PF3D7_1350100

基因描述

Type	Description
Definition	lysine--tRNA ligase

研究结论

Date	Results	Publications
2019-05-25 11:36:00	Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.	30894487
2014-02-01 10:39:00	crystal structure of lysyl-tRNA synthetase in the apo form	23633587

名称对应

Type	IDs
Synonymous	PF13_0262
Gene	UniProtKB-ID: Q8IDJ8_PLAF7 UniprotKB: Q8IDJ8 UniParc: UPI0000085533 EMBL: AL844509 EnsemblGenome: PF3D7_1350100 KO: pfa:PF3D7_1350100
Nucleutide sequences	EMBL-CDS: CAD52623.1 Gene_ORFName: PF3D7_1350100
Protein sequencees	RefSeq: XP_001350214.1
Others	UniRef100: UniRef100_A0A2I0BS57 UniRef90: UniRef90_W7JP72 UniRef50: UniRef50_W5N825

全选

{{proteinIndex+1}}	mRNA	Protein	UniprotKB	Description
Refseq	{{protein.nucleotideVersion}} Ensembl: {{protein.nucleotideEnsembl}}	{{protein.proteinVersion}} Ensembl: {{protein.proteinEnsembl}}	{{uniprot}}	Definition: {{{protein.definition}}} Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}}
Location	( {{protein.positionStart}}..{{protein.positionEnd}} )
Conserved domain	Region: {{conservedDomain.region == '' \|\| conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' \|\| conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' \|\| conservedDomain.family == null ? "-": conservedDomain.family}} CDD:	{{conservedDomain.comments == '' \|\| conservedDomain.comments == null ? "-" : conservedDomain.comments }}	Region: {{conservedDomain.region == '' \|\| conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' \|\| conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' \|\| conservedDomain.family == null ? "-": conservedDomain.family}} CDD:	{{conservedDomain.comments == '' \|\| conservedDomain.comments == null ? "-" : conservedDomain.comments }}

mRNA

Protein

UniprotKB

Description

Refseq

Ensembl: {{protein.nucleotideEnsembl}}

Ensembl: {{protein.proteinEnsembl}}

Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

( {{protein.positionStart}}..{{protein.positionEnd}} )

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全选

Pubmed编号	文献信息	发表日期	相关基因
30894487	Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proc Natl Acad Sci U S A Beatriz BaragaÃ±a , Barbara Forte , Ryan Choi , Stephen Nakazawa Hewitt , Juan A Bueren-Calabuig , JoÃ£o Pedro Pisco , Caroline Peet , David M Dranow , David A Robinson , Chimed Jansen , Neil R Norcross , Sumiti Vinayak , Mark Anderson , Carrie F Brooks , Caitlin A Cooper , Sebastian Damerow , Michael Delves , Karen Dowers , James Duffy , Thomas E Edwards , Irene Hallyburton , Benjamin G Horst , Matthew A Hulverson , Liam Ferguson , MarÃa BelÃ©n JimÃ©nez-DÃaz , Rajiv S Jumani , Donald D Lorimer , Melissa S Love , Steven Maher , Holly Matthews , Case W McNamara , Peter Miller , Sandra O'Neill , Kayode K Ojo , Maria Osuna-Cabello , Erika Pinto , John Post , Jennifer Riley , Matthias Rottmann , Laura M Sanz , Paul Scullion , Arvind Sharma , Sharon M Shepherd , Yoko Shishikura , Frederick R C Simeons , Erin E Stebbins , Laste Stojanovski , Ursula Straschil , Fabio K Tamaki , Jevgenia Tamjar , Leah S Torrie , AmÃ©lie Vantaux , BenoÃ®t Witkowski , Sergio Wittlin , Manickam Yogavel , Fabio Zuccotto , IÃ±igo Angulo-Barturen , Robert Sinden , Jake Baum , Francisco-Javier Gamo , Pascal MÃ¤ser , Dennis E Kyle , Elizabeth A Winzeler , Peter J Myler , Paul G Wyatt , David Floyd , David Matthews , Amit Sharma , Boris Striepen , Christopher D Huston , David W Gray , Alan H Fairlamb , Andrei V Pisliakov , Chris Walpole , Kevin D Read , Wesley C Van Voorhis , Ian H Gilbert	2019-04-02	-
23633587	Structural analysis of malaria-parasite lysyl-tRNA synthetase provides a platform for drug development. Acta Crystallogr. D Biol. Crystallogr. Sameena Khan , Ankur Garg , Noelia Camacho , Jason Van Rooyen , Anil Kumar Pole , Hassan Belrhali , Lluis Ribas de Pouplana , Vinay Sharma , Amit Sharma	2013-05-01	PF13_0262
12368867	Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature N Hall , A Pain , M Berriman , C Churcher , B Harris , D Harris , K Mungall , S Bowman , R Atkin , S Baker , A Barron , K Brooks , C O Buckee , C Burrows , I Cherevach , C Chillingworth , T Chillingworth , Z Christodoulou , L Clark , R Clark , C Corton , A Cronin , R Davies , P Davis , P Dear , F Dearden , J Doggett , T Feltwell , A Goble , I Goodhead , R Gwilliam , N Hamlin , Z Hance , D Harper , H Hauser , T Hornsby , S Holroyd , P Horrocks , S Humphray , K Jagels , K D James , D Johnson , A Kerhornou , A Knights , B Konfortov , S Kyes , N Larke , D Lawson , N Lennard , A Line , M Maddison , J McLean , P Mooney , S Moule , L Murphy , K Oliver , D Ormond , C Price , M A Quail , E Rabbinowitsch , M-A Rajandream , S Rutter , K M Rutherford , M Sanders , M Simmonds , K Seeger , S Sharp , R Smith , R Squares , S Squares , K Stevens , K Taylor , A Tivey , L Unwin , S Whitehead , J Woodward , J E Sulston , A Craig , C Newbold , B G Barrell	2002-10-03	MAL7P1.110, MAL7P1.113, MAL7P1.104, MAL7P1.93, MAL7P1.94, PF07_0005, PF07_0014, MAL7P1.162, MAL7P1.164, MAL7P1.4, MAL7P1.69, MAL7P1.73, MAL7P1.147, MAL7P1.150, MAL7P1.151, MAL7P1.161, MAL7P1.75, MAL7P1.81, MAL7P1.86, PF07_0021, PF07_0023, PF07_0027, PF07_0040, MAL7P1.137, MAL7P1.139, MAL7P1.145, PF07_0046, PF07_0047, PF07_0054, PF07_0057, PF07_0059, PF07_0062, PF07_0065, PF07_0070, PF07_0071, PfCDPK4, PF07_0073, PF07_0079, PF07_0080, PF07_0085, PF07_0086, PF07_0088, PF07_0091, PF07_0098, MAL7P1.130, PF07_0103, PF07_0105, PF07_0112, PF07_0115, PF07_0117, PF07_0123, MAL7P1.118, MAL7P1.12, MAL7P1.122, MAL7P1.20, PfCRT, MAL7P1.37, MAL7P1.38, MAL8P1.13, MAL8P1.131, MAL8P1.23, MAL8P1.12, MAL8P1.125, MAL8P1.128, MAL8P1.110, PF08_0055, PF08_0056, PF08_0059, PF08_0069, FeSOD, PF08_0075, PF08_0076, PF08_0084, PF08_0085, PF08_0096, PF08_0108, PF08_0126, PF08_0129, PF08_0132, PF08_0136b, MAL8P1.48, MAL8P1.51, MAL8P1.37, MAL8P1.40, MAL8P1.43, MAL8P1.108, MAL8P1.140, MAL8P1.3, MAL8P1.31, MAL8P1.32, MAL8P1.33, MAL8P1.76, MAL8P1.78, MAL8P1.83, MAL8P1.9, PF08_0006, PF08_0009, PF08_0011, PF08_0014

Pubmed编号

文献信息

发表日期

相关基因

30894487

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Proc Natl Acad Sci U S A Beatriz BaragaÃ±a , Barbara Forte , Ryan Choi , Stephen Nakazawa Hewitt , Juan A Bueren-Calabuig , JoÃ£o Pedro Pisco , Caroline Peet , David M Dranow , David A Robinson , Chimed Jansen , Neil R Norcross , Sumiti Vinayak , Mark Anderson , Carrie F Brooks , Caitlin A Cooper , Sebastian Damerow , Michael Delves , Karen Dowers , James Duffy , Thomas E Edwards , Irene Hallyburton , Benjamin G Horst , Matthew A Hulverson , Liam Ferguson , MarÃa BelÃ©n JimÃ©nez-DÃaz , Rajiv S Jumani , Donald D Lorimer , Melissa S Love , Steven Maher , Holly Matthews , Case W McNamara , Peter Miller , Sandra O'Neill , Kayode K Ojo , Maria Osuna-Cabello , Erika Pinto , John Post , Jennifer Riley , Matthias Rottmann , Laura M Sanz , Paul Scullion , Arvind Sharma , Sharon M Shepherd , Yoko Shishikura , Frederick R C Simeons , Erin E Stebbins , Laste Stojanovski , Ursula Straschil , Fabio K Tamaki , Jevgenia Tamjar , Leah S Torrie , AmÃ©lie Vantaux , BenoÃ®t Witkowski , Sergio Wittlin , Manickam Yogavel , Fabio Zuccotto , IÃ±igo Angulo-Barturen , Robert Sinden , Jake Baum , Francisco-Javier Gamo , Pascal MÃ¤ser , Dennis E Kyle , Elizabeth A Winzeler , Peter J Myler , Paul G Wyatt , David Floyd , David Matthews , Amit Sharma , Boris Striepen , Christopher D Huston , David W Gray , Alan H Fairlamb , Andrei V Pisliakov , Chris Walpole , Kevin D Read , Wesley C Van Voorhis , Ian H Gilbert

2019-04-02

23633587

Structural analysis of malaria-parasite lysyl-tRNA synthetase provides a platform for drug development.

Acta Crystallogr. D Biol. Crystallogr. Sameena Khan , Ankur Garg , Noelia Camacho , Jason Van Rooyen , Anil Kumar Pole , Hassan Belrhali , Lluis Ribas de Pouplana , Vinay Sharma , Amit Sharma

2013-05-01

PF13_0262

12368867

Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.

Nature N Hall , A Pain , M Berriman , C Churcher , B Harris , D Harris , K Mungall , S Bowman , R Atkin , S Baker , A Barron , K Brooks , C O Buckee , C Burrows , I Cherevach , C Chillingworth , T Chillingworth , Z Christodoulou , L Clark , R Clark , C Corton , A Cronin , R Davies , P Davis , P Dear , F Dearden , J Doggett , T Feltwell , A Goble , I Goodhead , R Gwilliam , N Hamlin , Z Hance , D Harper , H Hauser , T Hornsby , S Holroyd , P Horrocks , S Humphray , K Jagels , K D James , D Johnson , A Kerhornou , A Knights , B Konfortov , S Kyes , N Larke , D Lawson , N Lennard , A Line , M Maddison , J McLean , P Mooney , S Moule , L Murphy , K Oliver , D Ormond , C Price , M A Quail , E Rabbinowitsch , M-A Rajandream , S Rutter , K M Rutherford , M Sanders , M Simmonds , K Seeger , S Sharp , R Smith , R Squares , S Squares , K Stevens , K Taylor , A Tivey , L Unwin , S Whitehead , J Woodward , J E Sulston , A Craig , C Newbold , B G Barrell

2002-10-03

MAL7P1.110, MAL7P1.113, MAL7P1.104, MAL7P1.93, MAL7P1.94, PF07_0005, PF07_0014, MAL7P1.162, MAL7P1.164, MAL7P1.4, MAL7P1.69, MAL7P1.73, MAL7P1.147, MAL7P1.150, MAL7P1.151, MAL7P1.161, MAL7P1.75, MAL7P1.81, MAL7P1.86, PF07_0021, PF07_0023, PF07_0027, PF07_0040, MAL7P1.137, MAL7P1.139, MAL7P1.145, PF07_0046, PF07_0047, PF07_0054, PF07_0057, PF07_0059, PF07_0062, PF07_0065, PF07_0070, PF07_0071, PfCDPK4, PF07_0073, PF07_0079, PF07_0080, PF07_0085, PF07_0086, PF07_0088, PF07_0091, PF07_0098, MAL7P1.130, PF07_0103, PF07_0105, PF07_0112, PF07_0115, PF07_0117, PF07_0123, MAL7P1.118, MAL7P1.12, MAL7P1.122, MAL7P1.20, PfCRT, MAL7P1.37, MAL7P1.38, MAL8P1.13, MAL8P1.131, MAL8P1.23, MAL8P1.12, MAL8P1.125, MAL8P1.128, MAL8P1.110, PF08_0055, PF08_0056, PF08_0059, PF08_0069, FeSOD, PF08_0075, PF08_0076, PF08_0084, PF08_0085, PF08_0096, PF08_0108, PF08_0126, PF08_0129, PF08_0132, PF08_0136b, MAL8P1.48, MAL8P1.51, MAL8P1.37, MAL8P1.40, MAL8P1.43, MAL8P1.108, MAL8P1.140, MAL8P1.3, MAL8P1.31, MAL8P1.32, MAL8P1.33, MAL8P1.76, MAL8P1.78, MAL8P1.83, MAL8P1.9, PF08_0006, PF08_0009, PF08_0011, PF08_0014

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