| Type | Description |
|---|---|
| Definition | M1-family alanyl aminopeptidase |
| Date | Results | Publications |
|---|---|---|
| 2018-05-19 11:53:00 | The evaluation of a highly selective inhibitor of PfA-M1, over PfA-M17, active on Plasmodium parasites in vitro and in vivo, highlights the relevance of PfA-M1 in the biological development of the parasite as well as in the list of promising anti-malarial targets to be considered in combination with current or future anti-malarial drugs. | 28934959 |
| 2010-09-20 12:16:00 | results provide insights on PfA-M1 topology regarding key compartments of the infected red blood cells implications for the development of inhibitors targeting this plasmodial enzyme. | 20591164 |
| 2010-05-10 11:16:00 | Data suggest that detailed understanding of the PfA-M1 and PfA-M17 active sites permits a rational approach in the development of a unique class of two-target and/or combination antimalarial therapy. | 20133789 |
| Type | IDs |
|---|---|
| Synonymous | MAL13P1.56 |
| Gene |
UniProtKB-ID:
Q8IEK1_PLAF7
UniprotKB:
Q8IEK1
UniParc:
UPI0000001B76
EMBL:
AL844509
EnsemblGenome:
PF3D7_1311800
KO:
pfa:PF3D7_1311800
|
| Nucleutide sequences |
EMBL-CDS:
CAD52253.1
Gene_ORFName:
PF3D7_1311800
|
| Protein sequencees |
RefSeq:
XP_001349846.1
|
| Others |
UniRef100:
UniRef100_O96935
UniRef90:
UniRef90_O96935
UniRef50:
UniRef50_O96935
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 28934959 |
Malar. J. Lotfi Bounaadja , Marjorie Schmitt , Sébastien Albrecht , Elisabeth Mouray , Céline Tarnus , Isabelle Florent |
2017-09-21 | - |
| 21659511 |
J Biol Chem Daniel Ragheb , Seema Dalal , Kristin M Bompiani , W Keith Ray , Michael Klemba |
2011-08-05 | - |
| 20591164 |
Malar J Omid Azimzadeh , Cissé Sow , Marc Gèze , Julius Nyalwidhe , Isabelle Florent |
2010-06-30 | - |
| 20133789 |
Proc. Natl. Acad. Sci. U.S.A. Sheena McGowan , Christine A Oellig , Woldeamanuel A Birru , Tom T Caradoc-Davies , Colin M Stack , Jonathan Lowther , Tina Skinner-Adams , Artur Mucha , Pawel Kafarski , Jolanta Grembecka , Katharine R Trenholme , Ashley M Buckle , Donald L Gardiner , John P Dalton , James C Whisstock |
2010-02-09 |
LAP,
MAL13P1.56
|
| 19206106 |
Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome. Proteomics Kalpana Lal , Judith Helena Prieto , Elizabeth Bromley , Sanya J Sanderson , John R Yates , Jonathan M Wastling , Fiona M Tomley , Robert E Sinden |
2009-03-01 | - |
| 16267556 |
A protein interaction network of the malaria parasite Plasmodium falciparum. Nature Douglas J LaCount , Marissa Vignali , Rakesh Chettier , Amit Phansalkar , Russell Bell , Jay R Hesselberth , Lori W Schoenfeld , Irene Ota , Sudhir Sahasrabudhe , Cornelia Kurschner , Stanley Fields , Robert E Hughes |
2005-11-03 |
MAL7P1.109,
MAL7P1.19,
MAL7P1.10,
MAL7P1.102,
PF07_0006,
PF07_0012,
PF07_0016,
MAL7P1.167,
MAL7P1.17,
MAL7P1.170,
MAL7P1.171,
MAL7P1.172,
MAL7P1.173,
MAL7P1.174,
ERF2,
MAL7P1.7,
MAL7P1.147,
MAL7P1.155,
MAL7P1.16,
MAL7P1.160,
MAL7P1.76,
MAL7P1.77,
MAL7P1.81,
MAL7P1.86,
PF07_0020,
PF07_0021,
PF07_0023,
PF07_0024,
PF07_0026,
PF07_0029,
PF07_0033,
MAL7P1.132,
MAL7P1.134,
MAL7P1.141,
MAL7P1.145,
PF07_0042,
PF07_0043,
PF07_0044,
PF07_0047,
PF07_0053,
PF07_0056,
PF07_0057,
PF07_0062,
PF07_0066,
PF07_0067,
PF07_0071,
PfCDPK4,
PF07_0073,
PF07_0077,
PF07_0080,
PF07_0081,
PF07_0082,
PF07_0084,
PF07_0086,
PF07_0087,
PF07_0088,
PF07_0097,
PF07_0100,
PF07_0101,
MAL7P1.126,
MAL7P1.129,
MAL7P1.13,
PF07_0104,
PF07_0105,
PF07_0106,
PF07_0107,
PF07_0112,
PF07_0117,
PF07_0120,
PF07_0122,
PF07_0123,
ApiAP2,
MAL7P1.118,
MAL7P1.119,
MAL7P1.12,
MAL7P1.20,
PfORC2,
MAL7P1.24,
MAL7P1.30,
MAL7P1.37,
MAL7P1.38,
MAL8P1.103,
MAL8P1.104,
MAL8P1.23,
MAL8P1.111,
MAL8P1.113,
MAL8P1.12,
2255.m00020,
MAL8P1.125,
MAL8P1.127,
MAL8P1.128,
PF08_0054,
PF08_0055,
PF08_0058,
PF08_0059,
PF08_0060,
PF08_0068,
PF08_0075,
PF08_0076
|
| 12368867 |
Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature N Hall , A Pain , M Berriman , C Churcher , B Harris , D Harris , K Mungall , S Bowman , R Atkin , S Baker , A Barron , K Brooks , C O Buckee , C Burrows , I Cherevach , C Chillingworth , T Chillingworth , Z Christodoulou , L Clark , R Clark , C Corton , A Cronin , R Davies , P Davis , P Dear , F Dearden , J Doggett , T Feltwell , A Goble , I Goodhead , R Gwilliam , N Hamlin , Z Hance , D Harper , H Hauser , T Hornsby , S Holroyd , P Horrocks , S Humphray , K Jagels , K D James , D Johnson , A Kerhornou , A Knights , B Konfortov , S Kyes , N Larke , D Lawson , N Lennard , A Line , M Maddison , J McLean , P Mooney , S Moule , L Murphy , K Oliver , D Ormond , C Price , M A Quail , E Rabbinowitsch , M-A Rajandream , S Rutter , K M Rutherford , M Sanders , M Simmonds , K Seeger , S Sharp , R Smith , R Squares , S Squares , K Stevens , K Taylor , A Tivey , L Unwin , S Whitehead , J Woodward , J E Sulston , A Craig , C Newbold , B G Barrell |
2002-10-03 |
MAL7P1.110,
MAL7P1.113,
MAL7P1.104,
MAL7P1.93,
MAL7P1.94,
PF07_0005,
PF07_0014,
MAL7P1.162,
MAL7P1.164,
MAL7P1.4,
MAL7P1.69,
MAL7P1.73,
MAL7P1.147,
MAL7P1.150,
MAL7P1.151,
MAL7P1.161,
MAL7P1.75,
MAL7P1.81,
MAL7P1.86,
PF07_0021,
PF07_0023,
PF07_0027,
PF07_0040,
MAL7P1.137,
MAL7P1.139,
MAL7P1.145,
PF07_0046,
PF07_0047,
PF07_0054,
PF07_0057,
PF07_0059,
PF07_0062,
PF07_0065,
PF07_0070,
PF07_0071,
PfCDPK4,
PF07_0073,
PF07_0079,
PF07_0080,
PF07_0085,
PF07_0086,
PF07_0088,
PF07_0091,
PF07_0098,
MAL7P1.130,
PF07_0103,
PF07_0105,
PF07_0112,
PF07_0115,
PF07_0117,
PF07_0123,
MAL7P1.118,
MAL7P1.12,
MAL7P1.122,
MAL7P1.20,
PfCRT,
MAL7P1.37,
MAL7P1.38,
MAL8P1.13,
MAL8P1.131,
MAL8P1.23,
MAL8P1.12,
MAL8P1.125,
MAL8P1.128,
MAL8P1.110,
PF08_0055,
PF08_0056,
PF08_0059,
PF08_0069,
FeSOD,
PF08_0075,
PF08_0076,
PF08_0084,
PF08_0085,
PF08_0096,
PF08_0108,
PF08_0126,
PF08_0129,
PF08_0132,
PF08_0136b,
MAL8P1.48,
MAL8P1.51,
MAL8P1.37,
MAL8P1.40,
MAL8P1.43,
MAL8P1.108,
MAL8P1.140,
MAL8P1.3,
MAL8P1.31,
MAL8P1.32,
MAL8P1.33,
MAL8P1.76,
MAL8P1.78,
MAL8P1.83,
MAL8P1.9,
PF08_0006,
PF08_0009,
PF08_0011,
PF08_0014
|
| 12166515 |
Parasitology M Allary , J Schrevel , I Florent |
2002-07-01 |
MAL13P1.56
|
| 9879894 |
Mol. Biochem. Parasitol. I Florent , Z Derhy , M Allary , M Monsigny , R Mayer , J Schrével |
1998-11-30 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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