Type | Description |
---|---|
Definition | ring-exported protein 1 |
Date | Results | Publications |
---|---|---|
2019-02-02 12:34:00 | these data represent the first instance of low nanomolar inhibition of an essential Plasmodium falciparum enzyme through a 4-aminoquinoline and might encourage further investigation of PfEXP1 as a potential chloroquine target candidate. | 29324251 |
2016-11-05 10:22:00 | REX1 mutant parasites show deficient export of PfEMP1 to the red blood cell surface and reduced binding to the endothelial cell receptor, CD36; REX1 is predicted to form a largely alpha-helical structure, with a repetitive charge pattern in the repeat sequence domain, providing potential insights into the role of REX1 in Maurer's cleft sculpting | 26304012 |
2011-12-03 10:27:00 | Thus, loss of functional REX1 directly or indirectly ablates the assembly of the Plasmodium falciparum virulence complex, including PfEMP1 and KAHRP, at the surface of host erythrocytes. | 21696460 |
Type | IDs |
---|---|
Synonymous | PFI1735c |
Gene |
UniProtKB-ID:
Q8I2G1_PLAF7
UniprotKB:
Q8I2G1
UniParc:
UPI0000086332
EMBL:
AL844508
EnsemblGenome:
PF3D7_0935900
KO:
pfa:PF3D7_0935900
|
Nucleutide sequences |
EMBL-CDS:
CAD52033.1
Gene_ORFName:
PF3D7_0935900
|
Protein sequencees |
RefSeq:
XP_001352223.1
|
Others |
UniRef100:
UniRef100_A0A2I0BST0
UniRef90:
UniRef90_A0A0L1IFH8
UniRef50:
UniRef50_A0A060RT08
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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