| Type | Description |
|---|---|
| Definition | thioredoxin reductase |
| Date | Results | Publications |
|---|---|---|
| 2018-05-12 10:57:00 | A "Seleno Effect" Differentiates the Roles of Redox Active Cysteine Residues in Plasmodium falciparum Thioredoxin Reductase. | 29485860 |
| 2016-12-17 12:13:00 | Five compounds with significant PfTrxR inhibitory activity, with IC50 values ranging from 0.9-7.5 microM against the target enzyme, were found out of the Malaria Box. | 27043496 |
| 2016-03-26 11:46:00 | This review paper provides an overview of the structure and function of TrxR, and gives an overview of modeling Plasmodium infections in animals, and suggests the role of Trx functions in antimalarial drug resistance.. | 26111176 |
| 2013-12-14 10:34:00 | Functional analysis of amino acid residues involved in substrate binding and in the architecture of the intersubunit cavity of thioredoxin reductase, which is a known binding site for disulfide reductase inhibitors. | 23845423 |
| 2013-01-26 11:44:00 | the first crystal structure of recombinant P. falciparum thioredoxin reductase (PfTrxR) at 2.9A was presented. | 22889878 |
| Type | IDs |
|---|---|
| Synonymous | PF3D7_0923800.2, PFI1170c |
| Gene |
UniProtKB-ID:
TRXR2_PLAF7
UniprotKB:
P61076
UniParc:
UPI000035D5FF
EMBL:
AL844508,
AF508128
EnsemblGenome:
PF3D7_0923800.1
KO:
pfa:PF3D7_0923800.1
|
| Nucleutide sequences |
EMBL-CDS:
AAQ07981.1,
CAX64232.1
Gene_ORFName:
PFI1170c
EnsemblGenome_TRS:
CAX64232
|
| Protein sequencees |
EnsemblGenome_PRO:
CAX64232
RefSeq:
XP_024329017.1,
XP_002808951.1
|
| Others |
UniRef100:
UniRef100_P61076
UniRef90:
UniRef90_P61076
UniRef50:
UniRef50_P61076
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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