| Type | Description |
|---|---|
| Definition | multidrug resistance protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:29:00 | Molecular detection of drug resistant polymorphisms in Plasmodium falciparum isolates from Southwest, Nigeria. | 33109270 |
| 2019-06-15 11:02:00 | Spatio-temporal screening of Plasmodium population with PfMDR1 single nucleotide polymorphism accounts for its association with antimalarial susceptibility. | 29842979 |
| 2018-09-15 10:35:00 | N86Y mutation augments resistance to the artemisinin-based combination therapy partner drug amodiaquine and the former first-line agent chloroquine; N86Y increases parasite susceptibility to the partner drugs lumefantrine and mefloquine, and the active artemisinin metabolite dihydroartemisinin | 27189525 |
| 2018-03-03 11:38:00 | Pfmdr1 is a pivotal factor in malaria resistance to artemisinin combination therapies. (Review) | 28355493 |
| 2017-09-23 13:20:00 | Altered Plasmodium falciparum sensitivity to the antiretroviral protease inhibitor lopinavir associated with polymorphisms in PfMDR1. | 27821443 |
| Type | IDs |
|---|---|
| Synonymous | PFE1150w |
| Gene |
UniProtKB-ID:
Q7K6A5_PLAF7
UniprotKB:
Q7K6A5
UniParc:
UPI000000D3ED
EMBL:
AL844504
EnsemblGenome:
PF3D7_0523000
KO:
pfa:PF3D7_0523000
|
| Nucleutide sequences |
EMBL-CDS:
CAD51594.1
Gene_ORFName:
PF3D7_0523000
|
| Protein sequencees |
RefSeq:
XP_001351787.1
|
| Others |
UniRef100:
UniRef100_P13568
UniRef90:
UniRef90_P13568
UniRef50:
UniRef50_P13568
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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