| Type | Description |
|---|---|
| Definition | ras-related protein Rab-5A |
| Date | Results | Publications |
|---|---|---|
| 2018-01-20 12:03:00 | A steric clash between active site residues governs whether a GTPase utilizes the cis-Gln or the trans-Gln (from the GAP) for catalysis. As the cis-Gln encounters a steric clash, the Rab GTPases use the "dual finger" mechanism where the interacting GAP supplies a trans-Gln for catalysis. The cis-Gln of Rab5a overcomes the steric clash when it is stabilized by a nearby residue. | 29095572 |
| 2013-07-20 10:43:00 | Rab5 proteins dramatically mislocalize upon fosmidomycin treatment, consistent with a loss of protein prenylation. | 23223036 |
| Type | IDs |
|---|---|
| Synonymous | PFB0500c |
| Gene |
UniProtKB-ID:
O96193_PLAF7
UniprotKB:
O96193
UniParc:
UPI0000075C0C
EMBL:
LN999943
EnsemblGenome:
PF3D7_0211200
KO:
pfa:PF3D7_0211200
|
| Nucleutide sequences |
EMBL-CDS:
CZT98125.1
Gene_ORFName:
PF3D7_0211200
|
| Protein sequencees |
RefSeq:
XP_001349618.1
|
| Others |
UniRef100:
UniRef100_W7JN63
UniRef90:
UniRef90_A0A060RN45
UniRef50:
UniRef50_A0A1J1GPF0
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29095572 |
Structural plasticity mediates distinct GAP-dependent GTP hydrolysis mechanisms in Rab33 and Rab5. FEBS J. Soneya Majumdar , Abhishek Acharya , Balaji Prakash |
2017-12-01 | - |
| 23223036 |
Eukaryotic Cell Ruth Howe , Megan Kelly , John Jimah , Dana Hodge , Audrey R Odom |
2013-02-01 |
Rab5a,
Rab5c
|
| 22188458 |
Biol. Cell Fathia Ben Rached , Carinne Ndjembo-Ezougou , Syama Chandran , Hana Talabani , Hélène Yera , Vrushali Dandavate , Pierre Bourdoncle , Markus Meissner , Utpal Tatu , Gordon Langsley |
2012-01-01 | - |
| 18263733 |
Four distinct pathways of hemoglobin uptake in the malaria parasite Plasmodium falciparum. Proc. Natl. Acad. Sci. U.S.A. David A Elliott , Michael T McIntosh , H Dean Hosgood , Shuo Chen , Gina Zhang , Pavlina Baevova , Keith A Joiner |
2008-02-19 | - |
| 12657463 |
The Plasmodium falciparum family of Rab GTPases. Gene Emmanuel Quevillon , Tobias Spielmann , Karima Brahimi , Debasish Chattopadhyay , Edouard Yeramian , Gordon Langsley |
2003-03-13 |
Rab5b
|
| 12368867 |
Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature N Hall , A Pain , M Berriman , C Churcher , B Harris , D Harris , K Mungall , S Bowman , R Atkin , S Baker , A Barron , K Brooks , C O Buckee , C Burrows , I Cherevach , C Chillingworth , T Chillingworth , Z Christodoulou , L Clark , R Clark , C Corton , A Cronin , R Davies , P Davis , P Dear , F Dearden , J Doggett , T Feltwell , A Goble , I Goodhead , R Gwilliam , N Hamlin , Z Hance , D Harper , H Hauser , T Hornsby , S Holroyd , P Horrocks , S Humphray , K Jagels , K D James , D Johnson , A Kerhornou , A Knights , B Konfortov , S Kyes , N Larke , D Lawson , N Lennard , A Line , M Maddison , J McLean , P Mooney , S Moule , L Murphy , K Oliver , D Ormond , C Price , M A Quail , E Rabbinowitsch , M-A Rajandream , S Rutter , K M Rutherford , M Sanders , M Simmonds , K Seeger , S Sharp , R Smith , R Squares , S Squares , K Stevens , K Taylor , A Tivey , L Unwin , S Whitehead , J Woodward , J E Sulston , A Craig , C Newbold , B G Barrell |
2002-10-03 |
MAL7P1.110,
MAL7P1.113,
MAL7P1.104,
MAL7P1.93,
MAL7P1.94,
PF07_0005,
PF07_0014,
MAL7P1.162,
MAL7P1.164,
MAL7P1.4,
MAL7P1.69,
MAL7P1.73,
MAL7P1.147,
MAL7P1.150,
MAL7P1.151,
MAL7P1.161,
MAL7P1.75,
MAL7P1.81,
MAL7P1.86,
PF07_0021,
PF07_0023,
PF07_0027,
PF07_0040,
MAL7P1.137,
MAL7P1.139,
MAL7P1.145,
PF07_0046,
PF07_0047,
PF07_0054,
PF07_0057,
PF07_0059,
PF07_0062,
PF07_0065,
PF07_0070,
PF07_0071,
PfCDPK4,
PF07_0073,
PF07_0079,
PF07_0080,
PF07_0085,
PF07_0086,
PF07_0088,
PF07_0091,
PF07_0098,
MAL7P1.130,
PF07_0103,
PF07_0105,
PF07_0112,
PF07_0115,
PF07_0117,
PF07_0123,
MAL7P1.118,
MAL7P1.12,
MAL7P1.122,
MAL7P1.20,
PfCRT,
MAL7P1.37,
MAL7P1.38,
MAL8P1.13,
MAL8P1.131,
MAL8P1.23,
MAL8P1.12,
MAL8P1.125,
MAL8P1.128,
MAL8P1.110,
PF08_0055,
PF08_0056,
PF08_0059,
PF08_0069,
FeSOD,
PF08_0075,
PF08_0076,
PF08_0084,
PF08_0085,
PF08_0096,
PF08_0108,
PF08_0126,
PF08_0129,
PF08_0132,
PF08_0136b,
MAL8P1.48,
MAL8P1.51,
MAL8P1.37,
MAL8P1.40,
MAL8P1.43,
MAL8P1.108,
MAL8P1.140,
MAL8P1.3,
MAL8P1.31,
MAL8P1.32,
MAL8P1.33,
MAL8P1.76,
MAL8P1.78,
MAL8P1.83,
MAL8P1.9,
PF08_0006,
PF08_0009,
PF08_0011,
PF08_0014
|
| 12368864 |
Genome sequence of the human malaria parasite Plasmodium falciparum. Nature Malcolm J Gardner , Neil Hall , Eula Fung , Owen White , Matthew Berriman , Richard W Hyman , Jane M Carlton , Arnab Pain , Karen E Nelson , Sharen Bowman , Ian T Paulsen , Keith James , Jonathan A Eisen , Kim Rutherford , Steven L Salzberg , Alister Craig , Sue Kyes , Man-Suen Chan , Vishvanath Nene , Shamira J Shallom , Bernard Suh , Jeremy Peterson , Sam Angiuoli , Mihaela Pertea , Jonathan Allen , Jeremy Selengut , Daniel Haft , Michael W Mather , Akhil B Vaidya , David M A Martin , Alan H Fairlamb , Martin J Fraunholz , David S Roos , Stuart A Ralph , Geoffrey I McFadden , Leda M Cummings , G Mani Subramanian , Chris Mungall , J Craig Venter , Daniel J Carucci , Stephen L Hoffman , Chris Newbold , Ronald W Davis , Claire M Fraser , Bart Barrell |
2002-10-03 | - |
| 9804551 |
Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum. Science M J Gardner , H Tettelin , D J Carucci , L M Cummings , L Aravind , E V Koonin , S Shallom , T Mason , K Yu , C Fujii , J Pederson , K Shen , J Jing , C Aston , Z Lai , D C Schwartz , M Pertea , S Salzberg , L Zhou , G G Sutton , R Clayton , O White , H O Smith , C M Fraser , M D Adams , J C Venter , S L Hoffman |
1998-11-06 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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