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8125 ANP32A

8125

ANP32A

acidic nuclear phosphoprotein 32 family member A

protein-coding

Homo sapiens

基因描述

Type Description
Definition acidic nuclear phosphoprotein 32 family member A

研究结论

Date Results Publications
2021-04-03 13:34:00 Host ANP32A mediates the assembly of the influenza virus replicase. 33208942
2020-09-12 16:03:00 Molecular basis of host-adaptation interactions between influenza virus polymerase PB2 subunit and ANP32A. 32694517
2020-07-25 11:54:00 Avian ANP32A proteins harbor an additional 33 amino acids compared to human ANP32A proteins, which are crucial for their ability to support the avian-origin influenza virus polymerase. Species differences in ANP32A can restrict the host range of influenza virus. 31694956
2020-06-27 10:40:00 ANP32A and ANP32B mediate the export of unspliced or partially spliced viral mRNA via interactions with Rev and CRM1. 31444273
2020-06-27 10:17:00 The contribution of minimal asparagine ladder from the leucine-rich repeat protein pp32 to stability is tested and lattice rigidity and hydrogen bond character is investigated. Point substitutions of the two ladder asparagines of pp32 are strongly destabilizing and decrease the cooperativity of unfolding. Asparagine side chains are held in a very rigid, nondynamic structure, making a significant contribution to stability. 31347358

名称对应

Type IDs
Synonymous C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32
Gene
UniProtKB-ID: AN32A_HUMAN, A0A384P5U2_HUMAN
UniprotKB: P39687, A0A384P5U2
UniParc: UPI0000125027
EMBL: X75090, AK312703, BC007200, BT007436, AY349171, GQ900908, AF025684, AK223280, U73477, U60823, CH471082
Ensembl: ENSG00000140350
KO: hsa:8125
Nucleutide sequences
EMBL-CDS: AAB91548.1, AAH07200.1, CAA52981.1, AAB39706.1, AAQ79832.1, AAC50570.1, BAD97000.1, EAW77824.1, BAG35581.1, AAP36104.1, ADO22425.1
Ensembl_TRS: ENST00000465139
Protein sequencees
Ensembl_PRO: ENSP00000417864
RefSeq: NP_006296.1
Others
UniRef100: UniRef100_P39687
UniRef90: UniRef90_P39687
UniRef50: UniRef50_P39687
UniGene: Hs.458747
CCDS: CCDS45292.1

全选

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