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811029 PF3D7_1147800.1

811029

PF3D7_1147800.1

merozoite adhesive erythrocytic binding protein

protein-coding

Plasmodium falciparum 3D7

基因描述

Type Description
Definition merozoite adhesive erythrocytic binding protein

研究结论

Date Results Publications
2018-06-02 12:09:00 This study shows that AMA1 and MAEBL are important for P. falciparum sporozoites to perform typical functions necessary for infection of human hepatocytes. These two proteins therefore have important roles during infection at distinct points in the life cycle, including the blood, mosquito, and liver stages. 28371168
2010-01-21 00:00:00 The M2 domain was sequenced from 3D7 and lab isolates and African samples. No evidence of diversifying or positive selection was found in the pattern of base substitutions. 17688178
2010-01-21 00:00:00 mRNA processing and alternative splicing of maebl was developmentally regulated 15465047
2010-01-21 00:00:00 MAEBL is the first P. falciparum ligand experimentally determined to be essential for this important step in the life cycle where the vector becomes infectious for transmitting sporozoites to people 18509478
2009-02-05 12:39:00 The transmembrane isoform of Plasmodium falciparum MAEBL is essential for the invasion of Anopheles salivary glands 18509478

名称对应

Type IDs
Synonymous PF11_0486, PF3D7_1147800.2
Gene
UniProtKB-ID: Q8IHP3_PLAF7
UniprotKB: Q8IHP3
UniParc: UPI0000079FB3
EMBL: LN999945
EnsemblGenome: PF3D7_1147800.1
KO: pfa:PF3D7_1147800.1
Nucleutide sequences
EMBL-CDS: CZT99141.1
Gene_ORFName: PF3D7_1147800.1
Protein sequencees
RefSeq: XP_024329139.1, XP_001348153.1
Others
UniRef100: UniRef100_Q8IHP3
UniRef90: UniRef90_Q8IHP3
UniRef50: UniRef50_Q8IHP3

全选

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研究热度

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