PF3D7_1147500 - protein farnesyltransferase subunit beta-BMKCloudï½ç¾è¿å®¢äº

811026 PF3D7_1147500

基因描述

Type	Description
Definition	protein farnesyltransferase subunit beta

研究结论

Date	Results	Publications
2010-01-21 00:00:00	Data are consistent with protein farnesyltransferase (PFT) as the target of BMS-388891 in P. falciparum and suggest that PFT inhibitors should be combined with other antimalarial agents for effective therapy.	15661734

名称对应

Type	IDs
Synonymous	PF11_0483
Gene	UniProtKB-ID: Q8IHP6_PLAF7 UniprotKB: Q8IHP6 UniParc: UPI00004C9C9B EMBL: LN999945 EnsemblGenome: PF3D7_1147500 KO: pfa:PF3D7_1147500
Nucleutide sequences	EMBL-CDS: CZT99137.1 Gene_ORFName: PF3D7_1147500
Protein sequencees	RefSeq: XP_001348150.2
Others	UniRef100: UniRef100_W7JRW6 UniRef90: UniRef90_A0A0L7LZY3 UniRef50: UniRef50_A0A1A8YXK1

全选

{{proteinIndex+1}}	mRNA	Protein	UniprotKB	Description
Refseq	{{protein.nucleotideVersion}} Ensembl: {{protein.nucleotideEnsembl}}	{{protein.proteinVersion}} Ensembl: {{protein.proteinEnsembl}}	{{uniprot}}	Definition: {{{protein.definition}}} Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}}
Location	( {{protein.positionStart}}..{{protein.positionEnd}} )
Conserved domain	Region: {{conservedDomain.region == '' \|\| conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' \|\| conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' \|\| conservedDomain.family == null ? "-": conservedDomain.family}} CDD:	{{conservedDomain.comments == '' \|\| conservedDomain.comments == null ? "-" : conservedDomain.comments }}	Region: {{conservedDomain.region == '' \|\| conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' \|\| conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' \|\| conservedDomain.family == null ? "-": conservedDomain.family}} CDD:	{{conservedDomain.comments == '' \|\| conservedDomain.comments == null ? "-" : conservedDomain.comments }}

mRNA

Protein

UniprotKB

Description

Refseq

Ensembl: {{protein.nucleotideEnsembl}}

Ensembl: {{protein.proteinEnsembl}}

Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

( {{protein.positionStart}}..{{protein.positionEnd}} )

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全选

Pubmed编号	文献信息	发表日期	相关基因
15661734	Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum. J Biol Chem Richard T Eastman , John White , Oliver Hucke , Kevin Bauer , Kohei Yokoyama , Laxman Nallan , Debopam Chakrabarti , Christophe L M J Verlinde , Michael H Gelb , Pradipsinh K Rathod , Wesley C Van Voorhis	2005-04-08	-
12368864	Genome sequence of the human malaria parasite Plasmodium falciparum. Nature Malcolm J Gardner , Neil Hall , Eula Fung , Owen White , Matthew Berriman , Richard W Hyman , Jane M Carlton , Arnab Pain , Karen E Nelson , Sharen Bowman , Ian T Paulsen , Keith James , Jonathan A Eisen , Kim Rutherford , Steven L Salzberg , Alister Craig , Sue Kyes , Man-Suen Chan , Vishvanath Nene , Shamira J Shallom , Bernard Suh , Jeremy Peterson , Sam Angiuoli , Mihaela Pertea , Jonathan Allen , Jeremy Selengut , Daniel Haft , Michael W Mather , Akhil B Vaidya , David M A Martin , Alan H Fairlamb , Martin J Fraunholz , David S Roos , Stuart A Ralph , Geoffrey I McFadden , Leda M Cummings , G Mani Subramanian , Chris Mungall , J Craig Venter , Daniel J Carucci , Stephen L Hoffman , Chris Newbold , Ronald W Davis , Claire M Fraser , Bart Barrell	2002-10-03	-
12368867	Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature N Hall , A Pain , M Berriman , C Churcher , B Harris , D Harris , K Mungall , S Bowman , R Atkin , S Baker , A Barron , K Brooks , C O Buckee , C Burrows , I Cherevach , C Chillingworth , T Chillingworth , Z Christodoulou , L Clark , R Clark , C Corton , A Cronin , R Davies , P Davis , P Dear , F Dearden , J Doggett , T Feltwell , A Goble , I Goodhead , R Gwilliam , N Hamlin , Z Hance , D Harper , H Hauser , T Hornsby , S Holroyd , P Horrocks , S Humphray , K Jagels , K D James , D Johnson , A Kerhornou , A Knights , B Konfortov , S Kyes , N Larke , D Lawson , N Lennard , A Line , M Maddison , J McLean , P Mooney , S Moule , L Murphy , K Oliver , D Ormond , C Price , M A Quail , E Rabbinowitsch , M-A Rajandream , S Rutter , K M Rutherford , M Sanders , M Simmonds , K Seeger , S Sharp , R Smith , R Squares , S Squares , K Stevens , K Taylor , A Tivey , L Unwin , S Whitehead , J Woodward , J E Sulston , A Craig , C Newbold , B G Barrell	2002-10-03	MAL7P1.110, MAL7P1.113, MAL7P1.104, MAL7P1.93, MAL7P1.94, PF07_0005, PF07_0014, MAL7P1.162, MAL7P1.164, MAL7P1.4, MAL7P1.69, MAL7P1.73, MAL7P1.147, MAL7P1.150, MAL7P1.151, MAL7P1.161, MAL7P1.75, MAL7P1.81, MAL7P1.86, PF07_0021, PF07_0023, PF07_0027, PF07_0040, MAL7P1.137, MAL7P1.139, MAL7P1.145, PF07_0046, PF07_0047, PF07_0054, PF07_0057, PF07_0059, PF07_0062, PF07_0065, PF07_0070, PF07_0071, PfCDPK4, PF07_0073, PF07_0079, PF07_0080, PF07_0085, PF07_0086, PF07_0088, PF07_0091, PF07_0098, MAL7P1.130, PF07_0103, PF07_0105, PF07_0112, PF07_0115, PF07_0117, PF07_0123, MAL7P1.118, MAL7P1.12, MAL7P1.122, MAL7P1.20, PfCRT, MAL7P1.37, MAL7P1.38, MAL8P1.13, MAL8P1.131, MAL8P1.23, MAL8P1.12, MAL8P1.125, MAL8P1.128, MAL8P1.110, PF08_0055, PF08_0056, PF08_0059, PF08_0069, FeSOD, PF08_0075, PF08_0076, PF08_0084, PF08_0085, PF08_0096, PF08_0108, PF08_0126, PF08_0129, PF08_0132, PF08_0136b, MAL8P1.48, MAL8P1.51, MAL8P1.37, MAL8P1.40, MAL8P1.43, MAL8P1.108, MAL8P1.140, MAL8P1.3, MAL8P1.31, MAL8P1.32, MAL8P1.33, MAL8P1.76, MAL8P1.78, MAL8P1.83, MAL8P1.9, PF08_0006, PF08_0009, PF08_0011, PF08_0014

Pubmed编号

文献信息

发表日期

相关基因

15661734

Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum.

J Biol Chem Richard T Eastman , John White , Oliver Hucke , Kevin Bauer , Kohei Yokoyama , Laxman Nallan , Debopam Chakrabarti , Christophe L M J Verlinde , Michael H Gelb , Pradipsinh K Rathod , Wesley C Van Voorhis

2005-04-08

12368864

Genome sequence of the human malaria parasite Plasmodium falciparum.

Nature Malcolm J Gardner , Neil Hall , Eula Fung , Owen White , Matthew Berriman , Richard W Hyman , Jane M Carlton , Arnab Pain , Karen E Nelson , Sharen Bowman , Ian T Paulsen , Keith James , Jonathan A Eisen , Kim Rutherford , Steven L Salzberg , Alister Craig , Sue Kyes , Man-Suen Chan , Vishvanath Nene , Shamira J Shallom , Bernard Suh , Jeremy Peterson , Sam Angiuoli , Mihaela Pertea , Jonathan Allen , Jeremy Selengut , Daniel Haft , Michael W Mather , Akhil B Vaidya , David M A Martin , Alan H Fairlamb , Martin J Fraunholz , David S Roos , Stuart A Ralph , Geoffrey I McFadden , Leda M Cummings , G Mani Subramanian , Chris Mungall , J Craig Venter , Daniel J Carucci , Stephen L Hoffman , Chris Newbold , Ronald W Davis , Claire M Fraser , Bart Barrell

2002-10-03

12368867

Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.

Nature N Hall , A Pain , M Berriman , C Churcher , B Harris , D Harris , K Mungall , S Bowman , R Atkin , S Baker , A Barron , K Brooks , C O Buckee , C Burrows , I Cherevach , C Chillingworth , T Chillingworth , Z Christodoulou , L Clark , R Clark , C Corton , A Cronin , R Davies , P Davis , P Dear , F Dearden , J Doggett , T Feltwell , A Goble , I Goodhead , R Gwilliam , N Hamlin , Z Hance , D Harper , H Hauser , T Hornsby , S Holroyd , P Horrocks , S Humphray , K Jagels , K D James , D Johnson , A Kerhornou , A Knights , B Konfortov , S Kyes , N Larke , D Lawson , N Lennard , A Line , M Maddison , J McLean , P Mooney , S Moule , L Murphy , K Oliver , D Ormond , C Price , M A Quail , E Rabbinowitsch , M-A Rajandream , S Rutter , K M Rutherford , M Sanders , M Simmonds , K Seeger , S Sharp , R Smith , R Squares , S Squares , K Stevens , K Taylor , A Tivey , L Unwin , S Whitehead , J Woodward , J E Sulston , A Craig , C Newbold , B G Barrell

2002-10-03

MAL7P1.110, MAL7P1.113, MAL7P1.104, MAL7P1.93, MAL7P1.94, PF07_0005, PF07_0014, MAL7P1.162, MAL7P1.164, MAL7P1.4, MAL7P1.69, MAL7P1.73, MAL7P1.147, MAL7P1.150, MAL7P1.151, MAL7P1.161, MAL7P1.75, MAL7P1.81, MAL7P1.86, PF07_0021, PF07_0023, PF07_0027, PF07_0040, MAL7P1.137, MAL7P1.139, MAL7P1.145, PF07_0046, PF07_0047, PF07_0054, PF07_0057, PF07_0059, PF07_0062, PF07_0065, PF07_0070, PF07_0071, PfCDPK4, PF07_0073, PF07_0079, PF07_0080, PF07_0085, PF07_0086, PF07_0088, PF07_0091, PF07_0098, MAL7P1.130, PF07_0103, PF07_0105, PF07_0112, PF07_0115, PF07_0117, PF07_0123, MAL7P1.118, MAL7P1.12, MAL7P1.122, MAL7P1.20, PfCRT, MAL7P1.37, MAL7P1.38, MAL8P1.13, MAL8P1.131, MAL8P1.23, MAL8P1.12, MAL8P1.125, MAL8P1.128, MAL8P1.110, PF08_0055, PF08_0056, PF08_0059, PF08_0069, FeSOD, PF08_0075, PF08_0076, PF08_0084, PF08_0085, PF08_0096, PF08_0108, PF08_0126, PF08_0129, PF08_0132, PF08_0136b, MAL8P1.48, MAL8P1.51, MAL8P1.37, MAL8P1.40, MAL8P1.43, MAL8P1.108, MAL8P1.140, MAL8P1.3, MAL8P1.31, MAL8P1.32, MAL8P1.33, MAL8P1.76, MAL8P1.78, MAL8P1.83, MAL8P1.9, PF08_0006, PF08_0009, PF08_0011, PF08_0014

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