| Type | Description |
|---|---|
| Definition | cysteine proteinase falcipain 3 |
| Date | Results | Publications |
|---|---|---|
| 2013-07-20 12:20:00 | Further study revealed that hydrophobic interactions present both in falcipain-2 and falcipain-3 also play important roles in the activation of these enzymes | 23077573 |
| 2010-01-21 00:00:00 | These results are consistent with a principal role of falcipain-2 and falcipain-3 in the hydrolysis of hemoglobin by P. falciparum. | 19357776 |
| 2010-01-21 00:00:00 | synthesized in late trophozoites/early schizonts, targeted to food vacuole and activated sequentially to degrade hemoglobin in erythrocytic parasites. | 15664655 |
| 2010-01-21 00:00:00 | falcipains utilize a previously undescribed bipartite motif-dependent mechanism for targeting to a hydrolytic organelle | 17565983 |
| 2010-01-21 00:00:00 | A study evaluating the synthetic substrate and model inhibitor profiles of FP-2 and FP-3 as well as BP-2 (berghepain-2), an orthologue from the rodent parasite Plasmodium berghei, is presented. | 16776649 |
| Type | IDs |
|---|---|
| Synonymous | PF11_0162 |
| Gene |
UniProtKB-ID:
Q8IIL0_PLAF7
UniprotKB:
Q8IIL0
UniParc:
UPI000007A64D
EMBL:
LN999945
EnsemblGenome:
PF3D7_1115400
KO:
pfa:PF3D7_1115400
|
| Nucleutide sequences |
EMBL-CDS:
CZT98814.1
Gene_ORFName:
PF3D7_1115400
|
| Protein sequencees |
RefSeq:
XP_001347833.1
|
| Others |
UniRef100:
UniRef100_W7KER8
UniRef90:
UniRef90_A0A060RU18
UniRef50:
UniRef50_Q9N6S8
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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