| Type | Description |
|---|---|
| Definition | orotidine 5'-phosphate decarboxylase |
| Date | Results | Publications |
|---|---|---|
| 2019-01-05 10:47:00 | Re-refinement of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase as an important antimalarial drug target has been reported. | 30279319 |
| 2014-10-04 10:52:00 | Studied the multienzyme complex formation of human malaria parasite Plasmodium falciparum (P. falciparum) orotate phosphoribosyltransferase (OPRT) and orotidine 5'-monophosphate decarboxylase (OMPDC). | 24507637 |
| 2010-01-21 00:00:00 | The structure of PfODCase displays classic TIM-barrel fold characteristic of the enzyme. Both the phosphate-binding loop & the betaalpha5-loop have conformational flexibility, which may be associated with substrate capture & product release. | 18303855 |
| 2010-01-21 00:00:00 | The result suggests that the OPRT-OMPDC enzyme complex might have kinetic benefits and thermal stability significantly different from the monofunctional enzyme. | 19800871 |
| Type | IDs |
|---|---|
| Synonymous | PF10_0225 |
| Gene |
UniProtKB-ID:
Q8IJH3_PLAF7
UniprotKB:
Q8IJH3
UniParc:
UPI0000078FF3
EMBL:
LN999944
EnsemblGenome:
PF3D7_1023200
KO:
pfa:PF3D7_1023200
|
| Nucleutide sequences |
EMBL-CDS:
CZT98487.1
Gene_ORFName:
PF3D7_1023200
|
| Protein sequencees |
RefSeq:
XP_001347509.1
|
| Others |
UniRef100:
UniRef100_W7JM29
UniRef90:
UniRef90_A0A060RTU5
UniRef50:
UniRef50_A0A060RTU5
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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