| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel subfamily H member 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:38:00 | dysfunction of KCNH6 causes overstimulation of insulin secretion in the short term and beta cell failure in the long term. | 30590050 |
| 2015-08-01 10:32:00 | results indicated that downregulation of miR-224 suppressed cell growth and resulted in the enhancement of cell apoptosis through activation of the ERG2-BAK-induced apoptosis pathway | 25783051 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | 21048031 |
| 2010-01-21 00:00:00 | Transcripts for HERG1 were present in all adenomas and although transcripts for HERG2 and HERG3 were also detected, their expression level was more variable. | 12634931 |
| Type | IDs |
|---|---|
| Synonymous | ERG-2, ERG2, HERG2, Kv11.2, hERG-2 |
| Gene |
UniProtKB-ID:
KCNH6_HUMAN,
B4DKC0_HUMAN,
B4DPJ3_HUMAN,
J9JID4_HUMAN
UniprotKB:
Q9H252,
B4DKC0,
B4DPJ3,
J9JID4
UniParc:
UPI000058F422,
UPI00017A75EF,
UPI000012DCAB,
UPI00017A79A4,
UPI000002ACAA,
UPI000002ACAB
EMBL:
AK091877,
AC113554,
AF311913,
AK298363,
AK296498,
AK090969,
BC006334
Ensembl:
ENSG00000173826
KO:
hsa:81033
|
| Nucleutide sequences |
EMBL-CDS:
AAH06334.1,
BAC03764.1,
BAC03559.1,
AAG40871.1,
BAG59132.1,
BAG60605.1
Ensembl_TRS:
ENST00000583023,
ENST00000581784,
ENST00000580652,
ENST00000456941,
ENST00000314672
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000463533,
ENSP00000463830,
ENSP00000396900,
ENSP00000464672,
ENSP00000318212
RefSeq:
XP_011523611.1,
XP_016880667.1,
XP_011523613.1,
XP_016880669.1,
XP_016880664.1,
XP_011523615.1,
XP_011523610.1,
XP_016880666.1,
NP_110406.1,
XP_011523614.1,
NP_001265849.1,
NP_001265848.1,
NP_775115.1,
XP_016880668.1,
XP_011523612.1,
XP_016880665.1
|
| Others |
UniRef100:
UniRef100_B4DKC0,
UniRef100_J9JID4,
UniRef100_B4DPJ3,
UniRef100_Q9H252
UniRef90:
UniRef90_J9JID4,
UniRef90_Q9H252
UniRef50:
UniRef50_O54853
UniGene:
Hs.591177
CCDS:
CCDS11639.1,
CCDS11638.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30590050 |
From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion. Cell Rep Jin-Kui Yang , Jing Lu , Sha-Sha Yuan , Asan , Xi Cao , Hai-Yan Qiu , Ting-Ting Shi , Fang-Yuan Yang , Qian Li , Cui-Ping Liu , Qian Wu , Yu-Hui Wang , Hai-Xia Huang , Abudurexiti Kayoumu , Jian-Ping Feng , Rong-Rong Xie , Xiao-Rong Zhu , Chang Liu , Guang-Ran Yang , Ming-Rong Zhang , Chun-Lan Xie , Chen Chen , Bo Zhang , George Liu , Xiu-Qing Zhang , Aimin Xu |
2018-12-26 | - |
| 26503718 |
Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate. J. Gen. Physiol. Xiaofan Li , Andriy Anishkin , Hansi Liu , Damian B van Rossum , Sree V Chintapalli , Jessica K Sassic , David Gallegos , Kendra Pivaroff-Ward , Timothy Jegla |
2015-11-01 |
Elk,
KCNH8,
KCNH4,
KCNH3,
KCNH5,
KCNA2,
KCNH1,
KCNH2,
KCNQ1,
KCNH6,
KCNH7
|
| 25783051 |
MicroRNA-224 targets ERG2 and contributes to malignant progressions of meningioma. Biochem. Biophys. Res. Commun. Maomao Wang , Xiaodong Deng , Qi Ying , Tingyan Jin , Ming Li , Chong Liang |
2015-05-01 |
MIR224,
KCNH6
|
| 22412388 |
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. PLoS Genet. Eimear E Kenny , Itsik Pe'er , Amir Karban , Laurie Ozelius , Adele A Mitchell , Sok Meng Ng , Monica Erazo , Harry Ostrer , Clara Abraham , Maria T Abreu , Gil Atzmon , Nir Barzilai , Steven R Brant , Susan Bressman , Edward R Burns , Yehuda Chowers , Lorraine N Clark , Ariel Darvasi , Dana Doheny , Richard H Duerr , Rami Eliakim , Nir Giladi , Peter K Gregersen , Hakon Hakonarson , Michelle R Jones , Karen Marder , Dermot P B McGovern , Jennifer Mulle , Avi Orr-Urtreger , Deborah D Proctor , Ann Pulver , Jerome I Rotter , Mark S Silverberg , Thomas Ullman , Stephen T Warren , Matti Waterman , Wei Zhang , Aviv Bergman , Lloyd Mayer , Seymour Katz , Robert J Desnick , Judy H Cho , Inga Peter |
2012-01-01 |
LINC00492,
LINC01475,
PRG3,
UBD,
SNX20,
SLCO6A1,
COX15,
IL23R,
PUS10,
CYLD,
RDH10,
SBSPON,
NKX2-3,
TMEM17,
ZNF365,
SLC35D1,
EHBP1,
ACSL6,
GABBR1,
TCERG1L,
SERBP1,
CNNM1,
CPAMD8,
GOT1,
SLC43A3,
HLA-A,
HLA-F,
HLA-G,
HLA-H,
C2orf74,
IL3,
IL12RB2,
INPP5D,
C1orf141,
MOG,
AK3,
CUTC,
PEX13,
ATG16L1,
USP40,
PRG2,
PSMB10,
ENTPD7,
PTGER4,
REL,
RPL7,
SAG,
CCL1,
CCL2,
CCL7,
CCL8,
CCL11,
CCL13,
NOD2,
PAPOLG,
SLC22A4,
SCARNA5,
TERF1,
KCNH6,
SLC25A28,
KIAA1841,
ADO,
DGKD,
NKD1,
PDLIM4,
P4HA2,
KCNB2,
USP34
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21048031 |
Haematologica Delphine Casabonne , Oscar Reina , Yolanda Benavente , Nikolaus Becker , Marc Maynadié , Lenka Foretová , Pierluigi Cocco , Anna González-Neira , Alexandra Nieters , Paolo Boffetta , Jaap M Middeldorp , Silvia de Sanjose |
2011-02-01 | - |
| 16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
| 16382104 |
Pharmacol. Rev. George A Gutman , K George Chandy , Stephan Grissmer , Michel Lazdunski , David McKinnon , Luis A Pardo , Gail A Robertson , Bernardo Rudy , Michael C Sanguinetti , Walter Stühmer , Xiaoliang Wang |
2005-12-01 |
KCNH8,
KCNV2,
KCNG3,
KCNH4,
KCNH3,
KCNG2,
KCNV1,
KCNH5,
KCNA1,
KCNA2,
KCNA3,
KCNA4,
KCNA5,
KCNA6,
KCNA7,
KCNA10,
KCNB1,
KCNC1,
KCNC2,
KCNC3,
KCNC4,
KCND1,
KCND2,
KCND3,
KCNF1,
KCNG1,
KCNH1,
KCNH2,
KCNQ1,
KCNQ2,
KCNQ3,
KCNS1,
KCNS2,
KCNS3,
KCNQ5,
KCNH6,
KCNH7,
KCNQ4,
KCNG4,
KCNB2
|
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 15203218 |
Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. Genomics Glenn K Fu , Jonathan T Wang , Junming Yang , Janice Au-Young , Laura L Stuve |
2004-07-01 |
SGK2,
TRIM22,
ABCA7,
TUBB3,
CIB1,
DIDO1,
CORO1A,
SLC2A13,
SLC18B1,
COL4A1,
C3orf49,
CPA2,
ASB7,
CSF1R,
GPR156,
NLRP6,
B3GNT6,
ELANE,
ABCA2,
TPCN2,
FGA,
ANKRD26,
PLEKHA6,
ZNF423,
CBX6,
ATP6V1C2,
SNX32,
CBY1,
MXRA5,
CNTNAP2,
PDLIM3,
KCNK2,
ADAM11,
MYBPC1,
MYH3,
MYH9,
ZDHHC9,
GULP1,
PRKAG3,
MYO3A,
SDK2,
AIM1L,
BSDC1,
PPP1R10,
PPP2R4,
PLXNA3,
URGCP,
PRRG2,
SLC2A9,
ADCK1,
INF2,
CSMD1,
CYP4F62P,
WNK1,
SPTA1,
TFDP1,
CLEC3B,
TPO,
C4B,
XPNPEP2,
PRRG3,
CALCA,
MCTP1,
NAA40,
EPHX3,
LIMD2,
KCNH6,
ADAMTS10,
USP9X,
FCAMR,
ADGRV1,
FBN3,
RAB2B,
FCGBP,
HERC2,
DCLK1,
ADAMTSL1,
OPN4,
SEC22B
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员