| Type | Description |
|---|---|
| Definition | erythrocyte membrane protein 1, PfEMP1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:28:00 | In vitro selection for adhesion of Plasmodium falciparum-infected erythrocytes to ABO antigens does not affect PfEMP1 and RIFIN expression. | 32732983 |
| 2020-09-19 16:22:00 | Cholesterol bound Plasmodium falciparum co-chaperone 'PFA0660w' complexes with major virulence factor 'PfEMP1' via chaperone 'PfHsp70-x'. | 30804381 |
| 2020-02-15 13:47:00 | the diversity of the PfEMP1 sequences from field sample compared to reference sequences repositories, is reported. | 31251748 |
| 2019-09-21 11:02:00 | we have used a set of recently laboratory adapted ICAM-1-binding parasite isolates to generate sequence tags and, from these, to identify the full-length PfEMP1 being expressed by them. In a subset of the strains available we were able to produce validated, full-length var gene sequences and use these to conduct biophysical analyses of the ICAM-1 binding regions | 29459671 |
| 2019-01-26 12:40:00 | We show for the first time the presence of PfEMP1 in early stage P. falciparum iRBC-EVs and the effects of these EVs on primary human monocytes, uncovering a new mechanism of potential parasite pathogenesis and host interaction. | 29349926 |
| Type | IDs |
|---|---|
| Synonymous | PF10_0001 |
| Gene |
UniProtKB-ID:
Q8IK37_PLAF7
UniprotKB:
Q8IK37
UniParc:
UPI0000084CA0
EMBL:
LN999944
EnsemblGenome:
PF3D7_1000100
KO:
pfa:PF3D7_1000100
|
| Nucleutide sequences |
EMBL-CDS:
CZT98248.1
Gene_ORFName:
PF3D7_1000100
|
| Protein sequencees |
RefSeq:
XP_001347288.1
|
| Others |
UniRef100:
UniRef100_A0A2I0BR82
UniRef90:
UniRef90_W7K594
UniRef50:
UniRef50_W7K594
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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