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810 CALML3

810

CALML3

calmodulin like 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition calmodulin like 3

研究结论

Date Results Publications
2018-12-29 10:46:00 Metformin suppresses gastric cancer through stimulating Calml3 secretion from TAFs. 30320344
2018-09-01 10:17:00 UVB irradiation induced increase in apoptosis, production and Ca2+ concentration of human lens epithelial cells , in part, by downregulating the expression of CALML3 and involved oxidative stress, Ca2+, JNK1/2 and ERK1/2 signaling pathways, suggesting that investigating CALML3 may useful for developing cataract treatment. 29436594
2018-04-28 11:39:00 We identified calmodulin-like protein 3 (CALML3) as a key sensor of this SNP and a coregulator of ERalpha, which contributes to differential gene transcription regulation in an estrogen and SERM-dependent fashion. Furthermore, using CRISPR/Cas9-engineered ZR75-1 breast cancer cells with different ZNF423 SNP genotypes, striking differences in cellular responses to SERMs and inhibitors, alone or in combination 28821270
2018-03-24 10:35:00 Loss of CALML3 predicts shorter overall and relapse-free survival in postoperative hepatocellular carcinoma (HCC) patients, thus providing a prognostic biomarker and therapy target in HCC. 29445139
2013-12-28 10:49:00 Increased CALML3 expression in suprabasal layers is characteristic for differentiating keratinocytes in normal epidermis, and nuclear expression of CALML3 inversely correlates with expression of the proliferation marker Ki-67. 23638045

名称对应

Type IDs
Synonymous CLP
Gene
UniProtKB-ID: CALL3_HUMAN
UniprotKB: P27482
UniParc: UPI00000015FC
EMBL: M58026, AK313934, X13461, BC031889, CH471072, AL732437
Ensembl: ENSG00000178363
KO: hsa:810
Nucleutide sequences
EMBL-CDS: EAW86443.1, AAA36356.1, CAA31809.1, BAG36653.1, AAH31889.1
Ensembl_TRS: ENST00000315238
Protein sequencees
Ensembl_PRO: ENSP00000315299
RefSeq: NP_005176.1
Others
UniRef100: UniRef100_P27482
UniRef90: UniRef90_P27482
UniRef50: UniRef50_P05933
UniGene: Hs.239600
CCDS: CCDS7069.1

全选

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研究热度

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