| Type | Description |
|---|---|
| Definition | cyclin dependent kinase 2 associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 12:01:00 | A compelling relationship exists between high CDK2AP1 mRNA expression and lower TNM classification of breast cancer, which is consistent with CDK2AP1 having a tumour-suppressive function. | 30343278 |
| 2018-08-04 11:19:00 | Knockdown of CDK2AP1 in hESCs results in increased p53 and enhances differentiation and favors it over a self-renewal fate. | 29734353 |
| 2018-03-31 10:14:00 | DOC1 re-expression in oral cancer cells causes a reversal of EMT. DOC1 promotes NURD binding to a subset of target loci. | 28683324 |
| 2017-03-11 11:02:00 | The simultaneous overexpression of p12CDK2-AP1 and CD82 significantly suppressed the in vivo tumor growth. | 27349208 |
| 2016-02-06 12:21:00 | knockdown of CDK2AP1 in primary human fibroblasts reduced proliferation and induced premature senescence, with the observed phenotype being p53 dependent | 25785833 |
| Type | IDs |
|---|---|
| Synonymous | DOC1, DORC1, ST19, doc-1, p12DOC-1 |
| Gene |
UniProtKB-ID:
CDKA1_HUMAN
UniprotKB:
O14519
UniParc:
UPI00001FB91D,
UPI000000164E
EMBL:
AB006077,
DB465022,
AF006484,
AC068768,
BC034717
Ensembl:
ENSG00000111328
KO:
hsa:8099
|
| Nucleutide sequences |
EMBL-CDS:
AAH34717.1,
BAA22937.1,
AAC77831.1
Ensembl_TRS:
ENST00000618072,
ENST00000542174,
ENST00000261692,
ENST00000544658,
ENST00000535979,
ENST00000538446,
ENST00000652466
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000440729,
ENSP00000442565,
ENSP00000442502,
ENSP00000498286,
ENSP00000438561,
ENSP00000479982,
ENSP00000261692
RefSeq:
NP_001257363.1,
NP_004633.1,
NP_001257362.1
|
| Others |
UniRef100:
UniRef100_O14519
UniRef90:
UniRef90_O14519
UniRef50:
UniRef50_O14519
UniGene:
Hs.433201
CCDS:
CCDS58289.1,
CCDS9245.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员