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80979 Slc26a5

80979

Slc26a5

solute carrier family 26, member 5

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 26, member 5

研究结论

Date Results Publications
2020-10-24 14:01:00 Deletion of exons 17 and 18 in prestin's STAS domain results in loss of function. 31053797
2019-08-31 12:59:00 Oxidative stress inhibits the expression of Prestin protein, and the transcription mechanism is triggered to compensate for the loss of Prestin protein in HEI-OC1 cells. AP-2delta is one of the important TFs that suppresses transcription of the Prestin gene, and AP-2delta suppression further boosted Prestin mRNA activation under oxidative stress. 31297132
2018-02-10 11:42:00 response of endogenously expressed prestin in HEI-OC1 cells is different from the response of prestin expressed exogenously in non-auditory cells 26854618
2017-05-27 10:19:00 The IVS2-2A>G mutation in the Slc26a5 gene is insufficient to cause hearing loss in mice. 27232762
2016-12-24 11:47:00 Prestin expression imparts susceptibility to 2-hydroxypropyl-beta-cyclodextrin-induced hearing loss. 26903308

名称对应

Type IDs
Synonymous Pres, prestin
Gene
UniProtKB-ID: S26A5_MOUSE, Q32MT7_MOUSE, Q32MT6_MOUSE
UniprotKB: Q99NH7, Q32MT7, Q32MT6
UniParc: UPI00005DC6EA, UPI0000003AFC, UPI00005DC6E9
EMBL: AC125313, AY024359, CH466586, BC108987, AC113028, AF529192, BC108986
Ensembl: ENSMUSG00000029015
KO: mmu:80979
Nucleutide sequences
EMBL-CDS: EDL03187.1, AAO59381.1, AAG59999.2, AAI08987.1, AAI08988.1
Ensembl_TRS: ENSMUST00000030878, ENSMUST00000115176
Protein sequencees
Ensembl_PRO: ENSMUSP00000030878, ENSMUSP00000110830
RefSeq: NP_109652.3, NP_001276716.1, XP_006535881.1, NP_001276717.1
Others
UniRef100: UniRef100_Q32MT6, UniRef100_Q99NH7
UniRef90: UniRef90_Q9EPH0
UniRef50: UniRef50_Q9EPH0
UniGene: Mm.160370
CCDS: CCDS19109.1

全选

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研究热度

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