| Type | Description |
|---|---|
| Definition | Kv channel-interacting protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-15 13:00:00 | These findings establish MG53 as a novel regulator of KChIP2 and Ito,f by modulating NF-kappaB activity and reveal its critical role in electrophysiological remodeling in cardiac hypertrophy. | 30760025 |
| 2019-02-23 11:41:00 | we are investigating the effects of hyperoxia on atrial electrophysiology using whole-cell patch-clamp electrophysiology experiments along with assessment of Kv1.5, Kv4.2, and KChIP2 transcripts and protein profiles using real-time quantitative RT-PCR and Western blotting. | 29139549 |
| 2018-05-12 12:10:00 | although there is a baseline presence of KChIP2 in the nucleus both in vivo and in vitro, KChIP2 does not directly regulate transcriptional activity. Moreover, the nuclear transport of KChIP2 is not dependent on Ca(2+). Thus, KChIP2 does not function as a conventional transcription factor in the heart. | 27349185 |
| 2018-01-20 10:42:00 | KChIP2 expression does not appear to underlie the circadian rhythm in repolarization duration. | 27736193 |
| 2017-08-12 12:21:00 | the Kv4.2/KChIP2 interaction in cardiomyocytes is highly dynamic, with a clear KChIP2 gene dosage effect on Kv4 channel surface expression but not on inactivation gating. | 28141821 |
| Type | IDs |
|---|---|
| Synonymous | KChIP2 |
| Gene |
UniProtKB-ID:
KCIP2_MOUSE,
Q3YAB3_MOUSE,
A0A5F8MPB0_MOUSE,
Q3YAA4_MOUSE,
Q3YAB2_MOUSE,
Q3YAB1_MOUSE
UniprotKB:
Q9JJ69,
Q3YAB3,
A0A5F8MPB0,
Q3YAA4,
Q3YAB2,
Q3YAB1
UniParc:
UPI0000576817,
UPI0000576816,
UPI0000029437,
UPI00003BF8E3,
UPI0000029438,
UPI00000E8500,
UPI0003D72396,
UPI00005767BE
EMBL:
BC132215,
AB044571,
AY647241,
BC138496,
DQ148497,
AB044570,
DQ148498,
AJ278536,
DQ148496,
DQ148505,
AC149086,
AJ278537,
AJ278535,
AC131185,
AF439340,
AF439339,
AF439341
Ensembl:
ENSMUSG00000025221
KO:
mmu:80906
|
| Nucleutide sequences |
EMBL-CDS:
AAL32044.1,
BAA96738.1,
AAT68467.1,
AAL32045.1,
BAA96739.1,
AAL32046.1,
CAC82026.1,
CAC82023.1,
CAC82024.1,
AAZ77813.1,
AAZ77822.1,
AAZ77814.1,
AAI38497.1,
AAI32216.1,
AAZ77815.1
Ensembl_TRS:
ENSMUST00000086993,
ENSMUST00000162528,
ENSMUST00000239049,
ENSMUST00000079431,
ENSMUST00000161886
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000084215,
ENSMUSP00000125142,
ENSMUSP00000158890,
ENSMUSP00000078400,
ENSMUSP00000124482
RefSeq:
NP_001263287.1,
XP_006527533.1,
XP_006527532.1,
XP_017173804.1,
NP_663750.1,
NP_663749.1,
NP_109641.2
|
| Others |
UniRef100:
UniRef100_Q3YAB1,
UniRef100_Q3YAB2,
UniRef100_Q3YAA4,
UniRef100_A0A5F8MPB0,
UniRef100_Q3YAB3,
UniRef100_Q9JJ69
UniRef90:
UniRef90_Q9JM59-3,
UniRef90_Q9JM59,
UniRef90_D5LL09,
UniRef90_Q3YAA4
UniRef50:
UniRef50_Q8R426,
UniRef50_Q9JM59-3,
UniRef50_Q9JM59,
UniRef50_D5LL09
UniGene:
Mm.213204
CCDS:
CCDS38004.1,
CCDS70955.1,
CCDS29868.1,
CCDS50453.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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