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80905 Polh

80905

Polh

polymerase (DNA directed), eta (RAD 30 related)

protein-coding

Mus musculus

基因描述

Type Description
Definition polymerase (DNA directed), eta (RAD 30 related)

研究结论

Date Results Publications
2016-05-14 11:49:00 the functions of REV3L in maintaining cell viability, embryonic viability and genomic stability are directly dependent on its polymerase activity, and cannot be ameliorated by an additional deletion of pol eta. 26727495
2016-04-30 10:25:00 XP-V has a role in adipose tissue senescence and metabolic syndrome 26240351
2016-02-13 12:26:00 Increase in UV-induced mutations at both G:C and A:T pairs associated with PolH deficiency suggests that PolH contributes to accurate translesion synthesis (TLS) past both T- & C-containing dimers. 25733082
2013-01-12 10:49:00 POLH deficiency did not affect the frequency and patterns of C:G mutations and UNG POLH double deficiency showed an additive effect of single deficiency. 22960197
2012-12-08 10:07:00 REV1 and Polkappa are involved in DNA damage tolerance via Poleta-REV1 interaction when Poleta fails to bypass its cognate substrates. 22244149

名称对应

Type IDs
Synonymous RAD30A, XPV
Gene
UniProtKB-ID: POLH_MOUSE
UniprotKB: Q9JJN0
UniParc: UPI00000288C2
EMBL: AK036296, AB027128, AB037184
Ensembl: ENSMUSG00000023953
KO: mmu:80905
Nucleutide sequences
EMBL-CDS: BAA97570.1, BAA97585.1, BAC29375.1
Ensembl_TRS: ENSMUST00000024749
Protein sequencees
Ensembl_PRO: ENSMUSP00000024749
RefSeq: NP_001351876.1, NP_109640.1
Others
UniRef100: UniRef100_Q9JJN0
UniRef90: UniRef90_Q9JJN0
UniRef50: UniRef50_Q9Y253
UniGene: Mm.311585
CCDS: CCDS28822.1

全选

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研究热度

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