| Type | Description |
|---|---|
| Definition | endoplasmic reticulum aminopeptidase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:12:00 | Sex-specific differences in endoplasmic reticulum aminopeptidase 1 modulation influence blood pressure and renin-angiotensin system responses. | 31672933 |
| 2020-02-15 10:51:00 | ERAP1 has a role in cancer and is a promising therapeutic target for Hedgehog-driven tumors. | 31341163 |
| 2019-10-26 12:29:00 | ERAP1(-/-) mice may serve as a useful animal model for studying pathogenesis of intestinal, skeletal, and immunological manifestations of Ankylosing Spondylitis. | 30127455 |
| 2019-08-03 11:10:00 | Study in hepatocellular carcinoma mouse models shows that Erap1 is critically involved in the process of tumor rejection and assumes a dual role by independently operating on both sides. Direct presentation of two MHC-I-restricted epitopes of a cancer-driving transplantation rejection antigen through Erap1 moderately affected tumor rejection by adoptively transferred T-cell receptor gene-modified T cells in each case. | 29559473 |
| 2019-03-02 10:57:00 | The ERAP1 behaves similar to acute-phase proteins, which are secreted into the blood in response to infectious/inflammatory stimuli and are involved in enhancing NO synthesis as a host defense mechanism. | 30365037 |
| Type | IDs |
|---|---|
| Synonymous | A-LAP, ARTS-1, Arts1, ERAAP, PILSA, PILSAP |
| Gene |
UniProtKB-ID:
ERAP1_MOUSE
UniprotKB:
Q9EQH2
UniParc:
UPI0000003F9F
EMBL:
BC046610,
AK030329,
CH466563,
AB047552,
AF227511
Ensembl:
ENSMUSG00000021583
KO:
mmu:80898
|
| Nucleutide sequences |
EMBL-CDS:
BAB11982.1,
BAC26904.1,
EDL37102.1,
AAH46610.1,
AAG44260.1
Ensembl_TRS:
ENSMUST00000169114
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000133166
RefSeq:
NP_109636.1,
XP_036014121.1,
XP_006517539.1,
XP_030103331.1
|
| Others |
UniRef100:
UniRef100_Q9EQH2
UniRef90:
UniRef90_Q9JJ22
UniRef50:
UniRef50_Q9NZ08
UniGene:
Mm.83526
CCDS:
CCDS26647.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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