NPL - N-acetylneuraminate pyruvate lyase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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80896 NPL

基因描述

Type	Description
Definition	N-acetylneuraminate pyruvate lyase

研究结论

Date	Results	Publications
2010-01-21 00:00:00	3D structure model of N-acetylneuraminate lyase from human (hNAL, EC 4.1.3.3) was created and refined	19057931
2010-01-21 00:00:00	an NPL splice variant is mainly expressed in human liver, kidney and peripheral blood leukocytes	16147865

名称对应

Type	IDs
Synonymous	C112, C1orf13, NAL, NPL1
Gene	UniProtKB-ID: NPL_HUMAN, A0A087WZ70_HUMAN UniprotKB: Q9BXD5, A0A087WZ70 UniParc: UPI000043F347, UPI00000728AB, UPI0000ED8F9A, UPI0000203CF9, UPI0000E52737, UPI00001CE060 EMBL: AK313225, BC042003, AL355999, AF338436, AY336748, AL513344, BC034966, BC125051, BC058003 Ensembl: ENSG00000135838 KO: hsa:80896
Nucleutide sequences	EMBL-CDS: AAI25052.1, AAH58003.1, AAQ82432.1, BAG36036.1, AAK25795.1 Ensembl_TRS: ENST00000258317, ENST00000367553, ENST00000367552, ENST00000367555, ENST00000367554, ENST00000614468
Protein sequencees	Ensembl_PRO: ENSP00000356525, ENSP00000356526, ENSP00000356523, ENSP00000356524, ENSP00000258317, ENSP00000482415 RefSeq: NP_001186985.1, NP_001186980.1, NP_110396.1, NP_001186981.1, NP_001186979.1
Others	UniRef100: UniRef100_A0A087WZ70, UniRef100_Q9BXD5 UniRef90: UniRef90_Q9BXD5, UniRef90_A0A087WZ70 UniRef50: UniRef50_Q6NYR8, UniRef50_Q9BXD5 UniGene: Hs.496969, Hs.731792 CCDS: CCDS1350.1, CCDS55666.1, CCDS55667.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
31452512	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance. Elife Matthew F Pech , Linda E Fong , Jacqueline E Villalta , Leanne Jg Chan , Samir Kharbanda , Jonathon J O'Brien , Fiona E McAllister , Ari J Firestone , Calvin H Jan , Jeffrey Settleman	2019-08-27	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
26186194	The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin WÃ¼hr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi	2015-07-16	-
25416956	A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , AmÃ©lie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , JÃ¶rg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-LÃ¡szlÃ³ BarabÃ¡si , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal	2014-11-20	-
22692205	Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J Biol Chem Anne K Bergfeld , Oliver M T Pearce , Sandra L Diaz , Tho Pham , Ajit Varki	2012-08-17	-
21832049	Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. J Biol Chem Judit OlÃ¡h , Orsolya Vincze , DezsÃµ VirÃ³k , DÃ³ra Simon , Zsolt BozsÃ³ , NatÃ¡lia TÃµkÃ©si , IstvÃ¡n HorvÃ¡th , Emma Hlavanda , JÃ¡nos KovÃ¡cs , Anna Magyar , MÃ¡ria SzÅ©cs , Ferenc Orosz , Botond Penke , Judit OvÃ¡di	2011-09-30	-
19057931	Homology modeling and molecular dynamics study on N-acetylneuraminate lyase. J Mol Model Hui-Ying Chu , Qing-Chuan Zheng , Yong-Shan Zhao , Hong-Xing Zhang	2009-03-01	NPL
16710414	The DNA sequence and biological annotation of human chromosome 1. Nature S G Gregory , K F Barlow , K E McLay , R Kaul , D Swarbreck , A Dunham , C E Scott , K L Howe , K Woodfine , C C A Spencer , M C Jones , C Gillson , S Searle , Y Zhou , F Kokocinski , L McDonald , R Evans , K Phillips , A Atkinson , R Cooper , C Jones , R E Hall , T D Andrews , C Lloyd , R Ainscough , J P Almeida , K D Ambrose , F Anderson , R W Andrew , R I S Ashwell , K Aubin , A K Babbage , C L Bagguley , J Bailey , H Beasley , G Bethel , C P Bird , S Bray-Allen , J Y Brown , A J Brown , D Buckley , J Burton , J Bye , C Carder , J C Chapman , S Y Clark , G Clarke , C Clee , V Cobley , R E Collier , N Corby , G J Coville , J Davies , R Deadman , M Dunn , M Earthrowl , A G Ellington , H Errington , A Frankish , J Frankland , L French , P Garner , J Garnett , L Gay , M R J Ghori , R Gibson , L M Gilby , W Gillett , R J Glithero , D V Grafham , C Griffiths , S Griffiths-Jones , R Grocock , S Hammond , E S I Harrison , E Hart , E Haugen , P D Heath , S Holmes , K Holt , P J Howden , A R Hunt , S E Hunt , G Hunter , J Isherwood , R James , C Johnson , D Johnson , A Joy , M Kay , J K Kershaw , M Kibukawa , A M Kimberley , A King , A J Knights , H Lad , G Laird , S Lawlor , D A Leongamornlert , D M Lloyd , J Loveland , J Lovell , M J Lush , R Lyne , S Martin , M Mashreghi-Mohammadi , L Matthews , N S W Matthews , S McLaren , S Milne , S Mistry , M J F Moore , T Nickerson , C N O'Dell , K Oliver , A Palmeiri , S A Palmer , A Parker , D Patel , A V Pearce , A I Peck , S Pelan , K Phelps , B J Phillimore , R Plumb , J Rajan , C Raymond , G Rouse , C Saenphimmachak , H K Sehra , E Sheridan , R Shownkeen , S Sims , C D Skuce , M Smith , C Steward , S Subramanian , N Sycamore , A Tracey , A Tromans , Z Van Helmond , M Wall , J M Wallis , S White , S L Whitehead , J E Wilkinson , D L Willey , H Williams , L Wilming , P W Wray , Z Wu , A Coulson , M Vaudin , J E Sulston , R Durbin , T Hubbard , R Wooster , I Dunham , N P Carter , G McVean , M T Ross , J Harrow , M V Olson , S Beck , J Rogers , D R Bentley , R Banerjee , S P Bryant , D C Burford , W D H Burrill , S M Clegg , P Dhami , O Dovey , L M Faulkner , S M Gribble , C F Langford , R D Pandian , K M Porter , E Prigmore	2006-05-18	-
16147865	A novel splice variant of human gene NPL, mainly expressed in human liver, kidney and peripheral blood leukocyte. DNA Seq. Maoqing Wu , Shaohua Gu , Jian Xu , Xianqiong Zou , Huarui Zheng , Zhe Jin , Yi Xie , Chaoneng Ji , Yumin Mao	2005-04-01	NPL

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