| Type | Description |
|---|---|
| Definition | YEATS domain containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-06 10:58:00 | This study determined the crystal structure of the GAS41 YEATS domain with H3K23acK27ac to visualize the molecular basis of diacetylated histone binding. The results suggest a unique binding mode in which full-length GAS41 is a reader of diacetylated histones. | 30071723 |
| 2018-08-04 10:06:00 | Cellular and structural studies revealed that GAS41 is a histone lysine succinylation reader owing to a protonated histidine residue located inside the pocket. | 29463709 |
| 2018-06-09 10:42:00 | study identifies GAS41 as a histone acetylation reader that promotes histone H2A.Z deposition in non-small cell lung cancer. | 29437725 |
| 2018-03-10 12:03:00 | our study demonstrated the oncogenic roles of YEATS4 in the progression of pancreatic cancer by activating beta-catenin/TCF signaling and suggested that YEATS4 might be a promising therapeutic target for pancreatic cancer. | 28445953 |
| 2018-03-03 12:05:00 | Results showed that increased expression of YEATS4 might play a critical role in promoting GC cell proliferation and apoptosis by activating the Wnt/beta-catenin signaling pathway. | 28251887 |
| Type | IDs |
|---|---|
| Synonymous | 4930573H17Rik, B230215M10Rik, GAS41, NUBI-1, YAF9 |
| Gene |
UniProtKB-ID:
YETS4_HUMAN,
F8W0J4_HUMAN
UniprotKB:
O95619,
F8W0J4
UniParc:
UPI0000043800,
UPI0000E23280
EMBL:
AC117502,
AJ245746,
U61384,
BC000994,
AK001413
Ensembl:
ENSG00000127337
KO:
hsa:8089
|
| Nucleutide sequences |
EMBL-CDS:
BAA91678.1,
AAH00994.1,
CAC01935.1,
AAD12188.1
Ensembl_TRS:
ENST00000247843,
ENST00000548020
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000247843,
ENSP00000447199
RefSeq:
NP_001287879.1,
NP_006521.1
|
| Others |
UniRef100:
UniRef100_O95619,
UniRef100_F8W0J4
UniRef90:
UniRef90_F8W0J4,
UniRef90_O95619
UniRef50:
UniRef50_F8W0J4,
UniRef50_O95619
UniGene:
Hs.4029
CCDS:
CCDS8990.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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