| Type | Description |
|---|---|
| Definition | heat shock protein 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-13 11:30:00 | this study shows that Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress | 31047988 |
| 2020-03-28 11:52:00 | HSP22 reduces elevated lipid peroxidation levels and apoptosis during lung ischemia-reperfusion injury in mice. | 30922561 |
| 2019-06-29 10:35:00 | Results suggest that toxic gain-of-function of mutant Hspb8 aggregates is a major contributor to the peripheral neuropathy and the myopathy. In addition, mutant Hspb8 induces impairments in autophagy that may aggravate the phenotype. | 28780615 |
| 2019-02-09 11:51:00 | These results strongly suggest that HSP22 interacts with mTOR and regulates TNF-alpha-induced IL-6 synthesis in osteoblasts. | 29532456 |
| 2017-11-18 11:16:00 | HSP22 functions as a negative regulator in the TGF-beta-stimulated migration of osteoblasts. | 27396899 |
| Type | IDs |
|---|---|
| Synonymous | AU018630, AW413033, Cryac, D5Ucla4, E2IG1, H11, H11K, HSP20-like, HSP22 |
| Gene |
UniProtKB-ID:
HSPB8_MOUSE
UniprotKB:
Q9JK92
UniParc:
UPI0000001908
EMBL:
AF273453,
AK005052,
BC011219,
AF250139
Ensembl:
ENSMUSG00000041548
KO:
mmu:80888
|
| Nucleutide sequences |
EMBL-CDS:
AAF65563.1,
AAG00233.1,
AAH11219.1,
BAB23778.1
Ensembl_TRS:
ENSMUST00000036991
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037007
RefSeq:
NP_109629.1
|
| Others |
UniRef100:
UniRef100_Q9JK92
UniRef90:
UniRef90_Q9UJY1
UniRef50:
UniRef50_Q9UJY1
UniGene:
Mm.21549
CCDS:
CCDS19600.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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