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80877 Lrba

80877

Lrba

LPS-responsive beige-like anchor

protein-coding

Mus musculus

基因描述

Type Description
Definition LPS-responsive beige-like anchor

研究结论

Date Results Publications
2020-03-28 10:58:00 Lrba (-/-) DCs exhibited excessive IRF3/7- and PI3K/mTORC1-dependent signaling. 31097594
2019-03-16 12:28:00 LRBA role in olfaction.LRBA is expressed in olfactory and vomeronasal sensory neurons.LRBA is required for the efficient subcellular localization of a lipid-anchored protein, and of a ciliary protein. 28814779
2018-07-21 10:30:00 LRBA deficiency is associated with a reduced abundance of radixin and Nherf2, two adaptor proteins, which are important for the mechanical stability of the basal taper region of stereocilia. 28893864
2018-05-26 11:31:00 these studies revealed that LRBA has a critical, cell-autonomous role in promoting cytotoxic T-lymphocyte antigen-4 accumulation within CD4 effector T cells and FOXP3+ T-regulatory cells 28611475
2018-05-26 10:09:00 Lrba-/- mice displayed decreased cytotoxic T-lymphocyte-associated protein-4 expression by regulatory T cells and activated conventional CD4+ and CD8+ T lymphocytes, reduced frequency of peritoneal B-1a cells along with diminished interleukin-10 production and increased percentages of T follicular helper cells in Peyer's patches, but without developing overt signs of autoimmunity 28652580

名称对应

Type IDs
Synonymous C80285, D3Ertd775e, Lab300, Lba
Gene
UniProtKB-ID: LRBA_MOUSE, A0A0A6YXL6_MOUSE, E9Q3Y4_MOUSE, A0A0A6YXX3_MOUSE, Q8C7C2_MOUSE, Q8BSM6_MOUSE, Q8CBR4_MOUSE
UniprotKB: Q9ESE1, A0A0A6YXL6, E9Q3Y4, A0A0A6YXX3, Q8C7C2, Q8BSM6, Q8CBR4
UniParc: UPI0000E6B145, UPI00000EAC93, UPI000002782B, UPI000058B3FE, UPI00000E9480, UPI00000E8304, UPI00000E6EF3, UPI000024DE0E, UPI00000E9A26
EMBL: AF187731, AK052148, AF188507, AC104414, AF188506, AC102273, AC102164, AK031216, AC102270, AK035483, AC158386
Ensembl: ENSMUSG00000028080
KO: mmu:80877
Nucleutide sequences
EMBL-CDS: AAG15401.1, AAG15400.1, AAG14003.1, BAC34860.1, BAC27306.1, BAC29075.1
Ensembl_TRS: ENSMUST00000194759, ENSMUST00000107635, ENSMUST00000192145, ENSMUST00000195524
Protein sequencees
Ensembl_PRO: ENSMUSP00000142043, ENSMUSP00000103261, ENSMUSP00000142179, ENSMUSP00000141734
RefSeq: XP_006502410.1, NP_001071156.1, XP_006502416.1, XP_006502412.1, XP_006502414.1, XP_006502411.1, XP_006502415.1, NP_109620.2, XP_006502417.1, NP_001071155.1, XP_006502413.1
Others
UniRef100: UniRef100_E9Q3Y4, UniRef100_A0A0A6YXX3, UniRef100_A0A1D5RM41, UniRef100_Q9ESE1, UniRef100_A0A0A6YXL6, UniRef100_Q8CBR4, UniRef100_Q8BSM6
UniRef90: UniRef90_Q9ESE1, UniRef90_E9Q3Y4, UniRef90_Q8CBR4, UniRef90_F1M3T7, UniRef90_A0A0A6YXX3
UniRef50: UniRef50_F1M3T7, UniRef50_Q9ESE1, UniRef50_Q8CBR4, UniRef50_P50851
UniGene: Mm.439825

全选

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研究热度

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