| Type | Description |
|---|---|
| Definition | endonuclease/exonuclease/phosphatase family domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-07-21 10:41:00 | The mechanism by which RAD52 depletion causes synthetic lethality in BRCA1 mutant cancer cells depends on the 5' endonuclease EEPD1, which normally functions to cleave stressed replication forks to initiate HR repair. | 29145865 |
| 2017-07-08 11:00:00 | EEPD1 performs a gatekeeper function for replication fork repair by mediating the fork cleavage that permits initiation of HR-mediated repair and restart of stressed forks | 28049724 |
| 2017-06-24 10:27:00 | EEPD1 is a novel LXR-regulated gene in macrophages and that it promotes cellular cholesterol efflux by controlling cellular levels and activity of ABCA1. | 28082258 |
| 2016-06-11 10:18:00 | These data demonstrate that genome stability during replication stress is maintained by EEPD1, which initiates HR and inhibits cNHEJ and MMEJ. | 26684013 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | HSPC107 |
| Gene |
UniProtKB-ID:
EEPD1_HUMAN
UniprotKB:
Q7L9B9
UniParc:
UPI000020ED9D
EMBL:
CH236951,
AC078841,
AK027386,
BC065518,
AB051493,
AC007327,
CH471073
Ensembl:
ENSG00000122547
KO:
hsa:80820
|
| Nucleutide sequences |
EMBL-CDS:
AAH65518.1,
BAB55076.1,
BAB21797.1,
EAW94063.1,
EAL23976.1
Ensembl_TRS:
ENST00000242108,
ENST00000534978
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000442692,
ENSP00000242108
RefSeq:
XP_016868146.1,
NP_085139.2,
XP_016868147.1
|
| Others |
UniRef100:
UniRef100_Q7L9B9
UniRef90:
UniRef90_Q7L9B9
UniRef50:
UniRef50_Q7L9B9
UniGene:
Hs.487994,
Hs.670591
CCDS:
CCDS34619.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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