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8079 MLF2

8079

MLF2

myeloid leukemia factor 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition myeloid leukemia factor 2

研究结论

Date Results Publications
2021-03-20 13:26:00 Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF2. 32342107
2021-02-13 13:28:00 CRL4(DCAF8) and USP11 oppositely regulate the stability of myeloid leukemia factors (MLFs). 32703400
2017-11-04 11:56:00 Mutation in HTT causes Huntington's disease (HD); aggregates of mutated HTT cause apoptosis in neurons of HD patients. Data suggest that both MLF1 and MLF2 preferentially interact with mutated N-terminal HTT; MLF1/MLF2 reduce number of neurons (Neuro2A cell line) containing mutant HTT aggregates and subsequent apoptosis. (HTT = Huntingtin protein; MLF = myeloid leukemia factor) 27840155
2014-09-13 10:58:00 RPL39 and MLF2 have roles in tumor initiation and metastasis in breast cancer that involve nitric oxide synthase signaling 24876273
2008-03-13 08:55:00 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) 18095154

名称对应

Type IDs
Synonymous NTN4
Gene
UniProtKB-ID: MLF2_HUMAN, A8K1F4_HUMAN, Q5U0N1_HUMAN
UniprotKB: Q15773, A8K1F4, Q5U0N1
UniParc: UPI00015DA58D, UPI000012F1FA
EMBL: CR541700, BT019393, BC002340, AK289869, AF070539, CH471116, BC000898, U57342, BT019432, AK313998
Ensembl: ENSG00000089693
KO: hsa:8079
Nucleutide sequences
EMBL-CDS: AAH02340.1, AAB08988.1, AAC28632.1, AAH00898.1, BAF82558.1, BAG36710.1, CAG46501.1, EAW88744.1, AAV38200.1, EAW88743.1, AAV38239.1
Gene_ORFName: hCG_25928
Ensembl_TRS: ENST00000435120, ENST00000539187, ENST00000542154, ENST00000203630
Protein sequencees
Ensembl_PRO: ENSP00000403941, ENSP00000438671, ENSP00000203630, ENSP00000446317
RefSeq: NP_001369154.1, NP_005430.1, NP_001369155.1
Others
UniRef100: UniRef100_A8K1F4, UniRef100_Q15773
UniRef90: UniRef90_Q15773
UniRef50: UniRef50_Q15773
UniGene: Hs.524214
CCDS: CCDS8559.1

全选

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