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80760 ITIH5

80760

ITIH5

inter-alpha-trypsin inhibitor heavy chain family member 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition inter-alpha-trypsin inhibitor heavy chain family member 5

研究结论

Date Results Publications
2019-10-12 11:10:00 The results demonstrated that the MIR31HG-miR-31-ITIH5-PIK3CG pathway plays a role in the pathogenesis of Hirschsprung disease. 29626357
2018-11-24 11:36:00 ITIH5 may represent a novel modulator of TGF-beta superfamily signaling. 28940371
2018-02-10 10:52:00 Results provide evidence that ITIH5 triggers a reprogramming of breast cancer cells through global epigenetic changes effecting DAPK1. ITIH5 may represent an ECM modulator in epithelial breast tissue mediating suppression of tumor initiating cancer cell characteristics which are thought being responsible for the metastasis of breast cancer. 28231808
2017-09-16 10:53:00 Low ITIH5 expression is associated with liver metastasis in pancreatic cancer. 28289921
2017-09-09 13:29:00 This is the first study so far showing a putative tumor suppressive function of ITIH5 in cervical carcinogenesis. 28059468

名称对应

Type IDs
Synonymous ITI-HC5, PP14776
Gene
UniProtKB-ID: ITIH5_HUMAN, C9J2H1_HUMAN, G5E9D8_HUMAN, A0A096LP62_HUMAN, Q96JW9_HUMAN
UniprotKB: Q86UX2, C9J2H1, G5E9D8, A0A096LP62, Q96JW9
UniParc: UPI000013EA3E, UPI00017221A3, UPI00017221A4, UPI000006F295, UPI0000228862, UPI000014D02E, UPI0001E9ECA9, UPI0000048EC1
EMBL: AY358426, KF570249, AL158044, CR627109, AL355374, AK027831, AY238437, AK027375, AF318347, CH471072, AB075833
Ensembl: ENSG00000123243
KO: hsa:80760
Nucleutide sequences
EMBL-CDS: AAL55854.1, EAW86379.1, CAI12953.1, CAI12955.1, CAH10363.1, BAB85539.1, CAI16360.1, BAB55070.1, AAO49812.1, CAI16362.1, CAI16363.1, AAQ88792.1, EAW86383.1, BAB55397.1
Gene_ORFName: PP14776, UNQ311/PRO354, hCG_25113
Ensembl_TRS: ENST00000256861, ENST00000298441, ENST00000397146, ENST00000397145, ENST00000613909
Protein sequencees
Ensembl_PRO: ENSP00000256861, ENSP00000298441, ENSP00000380333, ENSP00000380332, ENSP00000485414
RefSeq: NP_116206.4, NP_085046.5, NP_001001851.1, XP_011518016.1, XP_011518015.1
Others
UniRef100: UniRef100_C9J2H1, UniRef100_Q96JW9, UniRef100_G5E9D8, UniRef100_Q86UX2, UniRef100_A0A096LP62
UniRef90: UniRef90_Q96JW9, UniRef90_Q86UX2-3, UniRef90_Q86UX2-2, UniRef90_Q86UX2
UniRef50: UniRef50_Q86UX2-3, UniRef50_Q86UX2, UniRef50_Q86UX2-2, UniRef50_A0A673TZC1
UniGene: Hs.498586, Hs.732936
CCDS: CCDS31139.2, CCDS31140.2

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