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80707 Wwox

80707

Wwox

WW domain-containing oxidoreductase

protein-coding

Mus musculus

基因描述

Type Description
Definition WW domain-containing oxidoreductase

研究结论

Date Results Publications
2021-02-06 13:50:00 Cigarette Smoke and Nicotine-Containing Electronic-Cigarette Vapor Downregulate Lung WWOX Expression, Which Is Associated with Increased Severity of Murine Acute Respiratory Distress Syndrome. 33058734
2020-12-26 13:14:00 Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3beta-mediated epileptic seizure activity in mice. 32000863
2020-04-18 12:10:00 The studies uncover an unforeseen role of the tumor suppressor WWOX in whole-body glucose homeostasis and highlight the intimate relationship between cancer progression and metabolic disorders, particularly obesity and type-2 diabetes. 30755385
2019-11-23 11:41:00 Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus. 30290271
2019-11-16 12:45:00 WWOX functions as a mammary tumor suppressor, likely through mediating genome stability in a p53-dependent mechanism, and its loss of function in mammary epithelium reproduces several important features of BLBCs. 30082886

名称对应

Type IDs
Synonymous 5330426P09Rik, 9030416C10Rik, WOX1
Gene
UniProtKB-ID: WWOX_MOUSE
UniprotKB: Q91WL8
UniParc: UPI0000194E9D, UPI00000E9894, UPI00000E8A26, UPI00000E8B3E
EMBL: AH011063, AK046903, AF187014, AK018507, AK078528, BC014716, AK019911
Ensembl: ENSMUSG00000004637
KO: mmu:80707
Nucleutide sequences
EMBL-CDS: BAB31911.1, BAC37325.1, AAH14716.1, BAC32916.1, AAF31693.1, BAB31244.1, AAL03972.1
Ensembl_TRS: ENSMUST00000109108, ENSMUST00000109107, ENSMUST00000160862, ENSMUST00000004756
Protein sequencees
Ensembl_PRO: ENSMUSP00000125626, ENSMUSP00000104735, ENSMUSP00000004756, ENSMUSP00000104736
RefSeq: XP_006531577.1, XP_006531573.1, XP_036010282.1, XP_006531574.1, XP_011246860.1, NP_062519.2, XP_006531575.1, XP_011246859.1, XP_006531576.1, XP_011246858.1, XP_036010283.1, XP_006531578.1
Others
UniRef100: UniRef100_Q91WL8
UniRef90: UniRef90_Q9NZC7
UniRef50: UniRef50_Q9NZC7
UniGene: Mm.440420
CCDS: CCDS22691.1

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