| Type | Description |
|---|---|
| Definition | SHOC2 leucine rich repeat scaffold protein |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:03:00 | SHOC2 is associated with the survival of breast cancer cells and has prognostic value for patients with breast cancer. | 31974612 |
| 2020-09-19 16:31:00 | Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers. | 31577942 |
| 2020-06-20 11:39:00 | miR-299-3p was significantly downregulated in thyroid cancer (TC) tissues and cell lines. miR-299-3p could inhibit cell proliferation and cell cycle progression, whereas remarkably promote cell apoptosis in TC cell lines. Bioinformatics predicted that SHOC2 might be a potential target of miR-299-3p. Subsequent Dual-Luciferase reporter analysis validated this hypothesis. | 30657565 |
| 2020-04-11 12:49:00 | Shoc2 single-domain antibodies can be used to understand functional mechanisms governing complex multiprotein signaling modules. | 31869742 |
| 2020-04-11 12:34:00 | study highlights a context-dependent contribution of SHOC2 to ERK pathway dynamics that is preferentially engaged by KRAS oncogenic signaling | 31213532 |
| Type | IDs |
|---|---|
| Synonymous | SIAA0862, SOC2, SUR8 |
| Gene |
UniProtKB-ID:
SHOC2_HUMAN
UniprotKB:
Q9UQ13
UniParc:
UPI00001F970E,
UPI0000135954
EMBL:
CH471066,
AL158163,
BC050445,
AK292833,
AF068920,
AB020669,
AK090820,
AF054828
Ensembl:
ENSG00000108061
KO:
hsa:8036
|
| Nucleutide sequences |
EMBL-CDS:
BAA74885.2,
AAC39856.1,
BAG52235.1,
AAH50445.1,
BAF85522.1,
AAC25698.1,
EAW49548.1
Ensembl_TRS:
ENST00000369452,
ENST00000265277
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265277,
ENSP00000358464
RefSeq:
NP_031399.2,
NP_001255968.1,
NP_001311266.1,
NP_001311265.1
|
| Others |
UniRef100:
UniRef100_Q9UQ13
UniRef90:
UniRef90_Q9UQ13
UniRef50:
UniRef50_Q9UQ13
UniGene:
Hs.104315
CCDS:
CCDS58095.1,
CCDS7568.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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