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80335 WDR82

80335

WDR82

WD repeat domain 82

protein-coding

Homo sapiens

基因描述

Type Description
Definition WD repeat domain 82

研究结论

Date Results Publications
2021-04-12 11:09:00 By making a stoichiometric complex with the RNA-binding protein ZC3H4, WDR82 controls termination of extragenic transcription in human and mouse cells. Cells depleted of the WDR82-ZC3H4 complex show greatly enhanced synthesis of long and spliced extragenic transcripts. 33767452
2016-03-19 10:19:00 these findings demonstrate that WDR82 is a negative regulator of virus-triggered type I IFNs pathway through mediating TRAF3 polyubiquitination status and stability on mitochondria. 26519536
2010-09-27 12:41:00 mammalian Wdr82 functions in a variety of cellular processes; PTW/PP1 phosphatase complex (PNUTS, Tox4, Wdr82, PP1) has a role in the regulation of chromatin structure during the transition from mitosis into interphase 20516061
2010-01-21 00:00:00 suggest a model for how the mammalian RNA polymerase II machinery is linked with histone H3-Lys4 histone methyltransferase complexes at transcriptionally active genes 17998332
2010-01-21 00:00:00 Data show that Wdr82, which associates with chromatin in a histone H2B ubiquitination-dependent manner, is a specific component of Set1 complexes but not that of MLL1-4 complexes. 18838538

名称对应

Type IDs
Synonymous MST107, MSTP107, PRO2730, PRO34047, SWD2, TMEM113, WDR82A
Gene
UniProtKB-ID: WDR82_HUMAN, A0A024R333_HUMAN
UniprotKB: Q6UXN9, A0A024R333
UniParc: UPI00000EBAC2
EMBL: AK074290, AY358264, CH471055, AK291380
Ensembl: ENSG00000164091
KO: hsa:80335
Nucleutide sequences
EMBL-CDS: EAW65202.1, AAQ88631.1, BAB85039.1, BAF84069.1, EAW65203.1
Gene_ORFName: UNQ9342/PRO34047, hCG_2000308
Ensembl_TRS: ENST00000296490
Protein sequencees
Ensembl_PRO: ENSP00000296490
RefSeq: XP_011532438.1, NP_079498.2
Others
UniRef100: UniRef100_Q6UXN9
UniRef90: UniRef90_Q6UXN9
UniRef50: UniRef50_Q6UXN9
UniGene: Hs.194110
CCDS: CCDS2851.2

全选

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