| Type | Description |
|---|---|
| Definition | ankyrin repeat and BTB domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 13:07:00 | Study demonstrates that miR-4319 is expressed at a low level in colorectal cancer (CRC) tissues, which predicts the poor clinical outcome of CRC. MiR-4319 regulates the proliferation, cell cycle, invasion and migration of CRC cells. Mechanically, miR-4319 is found to be transcriptionally regulated by PLZF, and acts as a tumour suppressor in CRC by targeting ABTB1. | 31065369 |
| 2010-01-21 00:00:00 | BPOZ-2 promoted eEF1A1 ubiquitylation and degradation, suggesting that eEF1A1 is a substrate of BPOZ-2. | 18459963 |
| 2010-01-21 00:00:00 | Study showed that BPOZ-2 is a human counterpart of yeast Btb3p, which is a putative adaptor for Pcu3p-based ubiquitin ligase; BPOZ-2 bound to E3 ligase CUL3 in vitro and in vivo. | 18429817 |
| Type | IDs |
|---|---|
| Synonymous | BPOZ, BTB3, BTBD21, EF1ABP, PP2259 |
| Gene |
UniProtKB-ID:
ABTB1_HUMAN
UniprotKB:
Q969K4
UniParc:
UPI000006E15D,
UPI0000035DA3,
UPI00001C119F,
UPI0000072357
EMBL:
AB053326,
AB053324,
AF447886,
AB053325,
BC011858,
CH471052,
AK130594,
AF297986
Ensembl:
ENSG00000114626
KO:
hsa:80325
|
| Nucleutide sequences |
EMBL-CDS:
BAB55649.1,
AAK57478.1,
BAB55648.1,
BAC85392.1,
AAH11858.1,
BAB55650.1,
EAW79334.1,
AAQ04661.1,
EAW79333.1
Gene_ORFName:
PP2259
Ensembl_TRS:
ENST00000232744,
ENST00000453791,
ENST00000468137
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000232744,
ENSP00000412684,
ENSP00000417366
RefSeq:
XP_016862774.1,
NP_115937.1,
XP_011511515.1,
XP_024309550.1,
XP_016862776.1,
XP_016862775.1,
XP_006713832.1,
NP_742024.1,
XP_024309551.1,
XP_016862777.1
|
| Others |
UniRef100:
UniRef100_Q969K4
UniRef90:
UniRef90_Q969K4
UniRef50:
UniRef50_Q969K4
UniGene:
Hs.107812
CCDS:
CCDS3045.1,
CCDS46901.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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