| Type | Description |
|---|---|
| Definition | centrosomal protein 70 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-31 10:55:00 | Cep70 interacts with tubulin, and promotes the ability of paclitaxel to stimulate microtubule assembly. These data demonstrate that Cep70 mediates paclitaxel sensitivity in breast cancer. | 28632150 |
| 2017-06-03 12:08:00 | these results demonstrate a critical role for Cep70 in the development and progression of breast cancer. | 28063737 |
| 2016-12-24 10:09:00 | Cep70 overexpression stimulates pancreatic cancer by inducing centrosome abnormality and microtubule disorganization | 26893288 |
| 2015-10-03 11:19:00 | findings suggest that Cep70 promotes microtubule stability by interaction with HDAC6 and regulation of tubulin acetylation | 26112604 |
| 2012-11-24 10:38:00 | data showed that Cep70 increased the microtubule length without affecting the microtubule number in the purified system; results demonstrate that Cep70 could directly regulate microtubule assembly by promoting microtubule elongation instead of microtubule nucleation | 22427462 |
| Type | IDs |
|---|---|
| Synonymous | BITE |
| Gene |
UniProtKB-ID:
CEP70_HUMAN,
A0A140VJG2_HUMAN,
B7Z2D2_HUMAN
UniprotKB:
Q8NHQ1,
A0A140VJG2,
B7Z2D2
UniParc:
UPI0000E08938,
UPI0001B79615,
UPI00004C2D1E,
UPI0002064EF1,
UPI00004C2D1D,
UPI000013D5A3
EMBL:
AC022497,
AK023098,
AK299003,
AF289495,
AK301913,
BC016050,
AC020890,
CH471052,
AK294587,
HM005349,
AF202146,
AC072045,
BC030598
Ensembl:
ENSG00000114107
KO:
hsa:80321
|
| Nucleutide sequences |
EMBL-CDS:
BAB14403.1,
EAW79063.1,
AAG35616.1,
AAH30598.1,
EAW79062.1,
AAG35791.1,
BAH12924.1,
BAH13584.1,
AAH16050.1,
AEE60949.1,
BAH11818.1
Ensembl_TRS:
ENST00000464035,
ENST00000474781,
ENST00000484888,
ENST00000264982,
ENST00000481834,
ENST00000489254
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264982,
ENSP00000419231,
ENSP00000419743,
ENSP00000419833,
ENSP00000417465,
ENSP00000417821
RefSeq:
XP_016862765.1,
XP_024309548.1,
XP_016862771.1,
XP_016862763.1,
NP_001275893.1,
XP_016862764.1,
XP_016862768.1,
NP_001307528.1,
NP_077817.2,
XP_016862767.1,
NP_001275894.1,
XP_016862761.1,
NP_001275896.1,
NP_001275895.1,
XP_016862770.1,
XP_016862760.1,
XP_011511511.1,
NP_001307527.1,
XP_016862766.1,
XP_016862773.1,
XP_016862769.1,
XP_024309549.1,
XP_016862772.1,
NP_001307529.1,
XP_016862762.1
|
| Others |
UniRef100:
UniRef100_B7Z2D2,
UniRef100_Q8NHQ1
UniRef90:
UniRef90_B7Z2D2,
UniRef90_Q8NHQ1
UniRef50:
UniRef50_Q8NHQ1,
UniRef50_A0A061I6D8
UniGene:
Hs.531962
CCDS:
CCDS82842.1,
CCDS3102.1,
CCDS75022.1,
CCDS75023.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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