| Type | Description |
|---|---|
| Definition | CDK5 regulatory subunit associated protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:43:00 | CDK5RAP3 as tumour suppressor negatively regulates self-renewal and invasion and is regulated by ERK1/2 signalling in human gastric cancer. | 32606358 |
| 2020-06-20 12:17:00 | The current findings advance innovation in drug discovery and highlight C53 as a novel pGC-B activator with sustained in vivo activity and anti-fibrotic actions in vitro. | 30954448 |
| 2019-08-31 11:07:00 | CDK5RAP3 is associated with autophagy and down-regulated in renal cancer. | 31061682 |
| 2019-07-06 10:41:00 | Study demonstrated that CDK5RAP3/C53 isoform d (IC53d) was upregulated in gastric cancer tissues and was associated with tumor Tstage. Furthermore, overexpression of IC53d promoted the proliferation, colony formation and G1/S phase transition of gastric cancer cells, leading to enhancement of tumorigenesis in vitro and in vivo. | 30864700 |
| 2019-05-11 10:16:00 | Our results demonstrated that CDK5RAP3 negatively regulates the Wnt/beta-catenin signaling pathway by repressing AKT phosphorylation, which leads to better survival of patients with gastric cancer. | 29540196 |
| Type | IDs |
|---|---|
| Synonymous | C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553 |
| Gene |
UniProtKB-ID:
CK5P3_HUMAN
UniprotKB:
Q96JB5
UniParc:
UPI00020655A1,
UPI00000723B0,
UPI00000718B7,
UPI000007236F
EMBL:
CH471109,
AC018521,
BC072435,
AB062433,
AF217982,
AK023722,
AK300643,
BC009957,
AK223387,
AF110322,
AF343090
Ensembl:
ENSG00000108465
KO:
hsa:80279
|
| Nucleutide sequences |
EMBL-CDS:
AAG17225.1,
EAW94772.1,
BAD97107.1,
AAG39277.1,
EAW94775.1,
BAB14657.1,
BAH13320.1,
AAH09957.1,
EAW94778.1,
EAW94774.1,
AAK69655.1,
BAB93496.1,
AAH72435.1
Gene_ORFName:
MSTP016,
PP1553,
OK/SW-cl.114
Ensembl_TRS:
ENST00000338399,
ENST00000536708
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344683,
ENSP00000438886
RefSeq:
NP_001265146.1,
XP_016880655.1,
NP_001265126.1,
XP_011523599.1,
NP_001265127.1,
NP_001265145.1,
XP_016880653.1,
NP_788276.1,
XP_016880654.1
|
| Others |
UniRef100:
UniRef100_Q96JB5
UniRef90:
UniRef90_Q96JB5
UniRef50:
UniRef50_Q96JB5
UniGene:
Hs.20157
CCDS:
CCDS62232.1,
CCDS42356.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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