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80273 GRPEL1

80273

GRPEL1

GrpE like 1, mitochondrial

protein-coding

Homo sapiens

基因描述

Type Description
Definition GrpE like 1, mitochondrial

研究结论

Date Results Publications
2020-04-04 12:19:00 These data demonstrate that LIV-1-GRPEL1 axis dually regulates mitotic exit as well as apoptosis by interacting with PP2A B55alpha and AIF. 31636012
2017-11-26 00:32:00 Data suggest that two putative NEF (nucleotide exchange factors) orthologs, GRPEL1 and GRPEL2, modulate function of mitochondrial HSP70 (mtHSP70); both GRPEL1 and GRPEL2 associate with mtHSP70 as hetero-oligomeric subcomplex and regulate mtHSP70 transport. (GRPEL = mitochondrial GrpE-like protein; HSP70 = heat-shock protein 70) 28848044
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 20877624
2010-01-21 00:00:00 The low resolution structure of human GrpE presented suggests that GrpE is a symmetric dimer when not bound to DnaK 12840016

名称对应

Type IDs
Synonymous GrpE, HMGE, mt-GrpE#1
Gene
UniProtKB-ID: GRPE1_HUMAN
UniprotKB: Q9HAV7
UniParc: UPI000012BA91
EMBL: CH471131, AF298592, BC024242, AL542571, AF087896, AK312882
Ensembl: ENSG00000109519
KO: hsa:80273
Nucleutide sequences
EMBL-CDS: AAP97195.1, BAG35730.1, AAH24242.1, AAG31605.1, EAW82371.1
Ensembl_TRS: ENST00000264954
Protein sequencees
Ensembl_PRO: ENSP00000264954
RefSeq: NP_079472.1
Others
UniRef100: UniRef100_Q9HAV7
UniRef90: UniRef90_Q9HAV7
UniRef50: UniRef50_Q9HAV7
UniGene: Hs.443723
CCDS: CCDS3396.1

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